Cholesterol 3-sulfate sodium salt (CAS 2864-50-8)
QUICK LINKS
Cholesterol 3-sulfate sodium salt is a white crystalline compound soluble in water, ethanol, and methanol used as a biological detergent, specifically in solubilizing lipids and membrane proteins. This negatively charged detergent has emerged as a beneficial replacement to existing detergent solutions due to its efficacy. It plays a pivotal role in membrane protein research, enabling the extraction of membrane proteins from a variety of organisms, such as bacteria and eukaryotic cells, without altering their structural integrity and functionality. Cholesterol 3-sulfate sodium salt has also been used to isolate high-quality protein crystals and for other molecular biology applications. Cholesterol 3-sulfate sodium salt activates multiple protein kinase C (PKC) iso-enzymes, especially the epsilon, eta and zeta isoforms.
Cholesterol 3-sulfate sodium salt (CAS 2864-50-8) References
- High-sensitivity negative-ion laser spray for liquid chromatography/mass spectrometry. | Hiraoka, K., et al. 2001. Rapid Commun Mass Spectrom. 15: 2020-6. PMID: 11675669
- Laser spray: electric field-assisted matrix-assisted laser desorption/ionization. | Hiraoka, K. 2004. J Mass Spectrom. 39: 341-50. PMID: 15103647
- Denaturation of lysozyme and myoglobin in laser spray. | Takamizawa, A., et al. 2005. J Am Soc Mass Spectrom. 16: 860-8. PMID: 15907701
- Sulfated glycosphingolipid as mediator of phagocytosis: SM4s enhances apoptotic cell clearance and modulates macrophage activity. | Popovic, ZV., et al. 2007. J Immunol. 179: 6770-82. PMID: 17982067
- The Rheological Properties of Lipid Monolayers Modulate the Incorporation of l-Ascorbic Acid Alkyl Esters. | Díaz, Yde L., et al. 2016. Langmuir. 32: 587-95. PMID: 26694518
- Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids. | Sanchez, LM., et al. 2016. PLoS One. 11: e0149603. PMID: 26992172
- Crossregulation between the insertion of Hexadecylphosphocholine (miltefosine) into lipid membranes and their rheology and lateral structure. | Zulueta Díaz, YLM. and Fanani, ML. 2017. Biochim Biophys Acta Biomembr. 1859: 1891-1899. PMID: 28642044
- A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria. | Yao, L., et al. 2022. Nat Microbiol. 7: 1404-1418. PMID: 35982310
- Cholesterol sulfate, a novel activator for the eta isoform of protein kinase C. | Ikuta, T., et al. 1994. Cell Growth Differ. 5: 943-7. PMID: 7819131
- Cholesterol sulfate activates multiple protein kinase C isoenzymes and induces granular cell differentiation in cultured murine keratinocytes. | Denning, MF., et al. 1995. Cell Growth Differ. 6: 1619-26. PMID: 9019167
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cholesterol 3-sulfate sodium salt, 5 mg | sc-202538 | 5 mg | $56.00 | |||
Cholesterol 3-sulfate sodium salt, 25 mg | sc-202538A | 25 mg | $107.00 |