Carnosic acid (CAS 3650-09-7)

Thank you for your question. The smallest quantity we can provide of Carnosic acid: sc-202520 is 10 mg.

Thank you for your question. We are unable to offer any specific recommendation on how to use Carnosic acid (CAS#3650-09-7) for cell culture studies. This product has not been specifically tested for cell culture use and is not cell culture grade, however, most products can still be used in cell culture applications by following basic cell culture protocols, e.g. using cell culture grade/sterilized solvents, aseptic technique, and sterilely filtering in a sterile hood. [If there is a graded product that you would like us to consider adding, please provide a technical service representative with all of the pertinent information needed including, name, CAS number, size, number of vials needed, grade/expected uses, and any additional information like, purity/potency and native source.] We would recommend you search in the primary literature to see how other investigators are using the chemical for this purpose. There are a few references listed on our website that may be a useful place to start your research: 1. Aruoma, O I., et al., 1992. Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid. Xenobiotica; the fate of foreign compounds in biological systems. 22(2): 257-68. PMID: 1378672 2. Schwarz, K., et al., 1992. Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. II. Isolation of carnosic acid and formation of other phenolic diterpenes. Zeitschrift für Lebensmittel-Untersuchung und -Forschung. 195(2): 99-103. PMID: 1529648 3. Haraguchi, H., et al., 1995. Inhibition of lipid peroxidation and superoxide generation by diterpenoids from Rosmarinus officinalis. Planta medica. 61(4): 333-6. PMID: 7480180 4. Geoffroy, M., et al., 1994. Radical intermediates and antioxidants: an ESR study of radicals formed on carnosic acid in the presence of oxidized lipids. Free radical research. 21(4): 247-58. PMID: 7827696 5. Kuzmenko, A I., et al., 1999. Chemiluminescence determination of the in vivo and in vitro antioxidant activity of RoseOx and carnosic acid. Journal of photochemistry and photobiology. B, Biology. 48(1): 63-7. PMID: 10205880 6. Rau, Oliver., et al., 2006. Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated receptor gamma. Planta medica. 72(10): 881-7. PMID: 16858665 If you have any further questions, please contact our European Technical Service team. You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: europe@scbt.com or by live chat directly on our website, www.scbt.com