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Carboxymethylcellulose, Sodium Salt (CAS 9004-32-4)

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Alternate Names:
Aquaplast; Sodium carboxymethylcellulose
Application:
Carboxymethylcellulose, Sodium Salt is a cellulase substrate
CAS Number:
9004-32-4
Molecular Formula:
[C6H7O2(OH)x•(C2H2O3Na)y]n
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Carboxymethyl cellulose (CMC) or cellulose gum is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone. Carboxymethylcellulose, Sodium Salt is the most often used form of cellulose gum. CMC is used in a variety of industries as a thickener and/or to prepare stable emulsions in both food and non-food products. Insoluble microgranular CMC is used as a cation-exchange resin in ion-exchange chromatography for purification of proteins. Carboxymethyl cellulose has also been used extensively to characterize enzyme activity from endoglucanases (part of the cellulase complex).


Carboxymethylcellulose, Sodium Salt (CAS 9004-32-4) References

  1. Alginate microparticles for enzyme peroral administration.  |  Coppi, G., et al. 2002. Int J Pharm. 242: 263-6. PMID: 12176260
  2. Characterization and superficial transformations on mini-matrices made of interpolymer complexes of chitosan and carboxymethylcellulose during in vitro clarithromycin release.  |  Gómez-Burgaz, M., et al. 2009. Eur J Pharm Biopharm. 73: 130-9. PMID: 19406235
  3. Characterization and bisphenol A adsorption capacity of β-cyclodextrin-carboxymethylcellulose-based hydrogels.  |  Kono, H., et al. 2013. Carbohydr Polym. 98: 784-92. PMID: 23987413
  4. Microparticles based on chitosan/carboxymethylcellulose polyelectrolyte complexes for colon delivery of vancomycin.  |  Cerchiara, T., et al. 2016. Carbohydr Polym. 143: 124-30. PMID: 27083351
  5. Rapid Development of Wet Adhesion between Carboxymethylcellulose Modified Cellulose Surfaces Laminated with Polyvinylamine Adhesive.  |  Gustafsson, E., et al. 2016. ACS Appl Mater Interfaces. 8: 24161-7. PMID: 27552256
  6. Amidated pectin/sodium carboxymethylcellulose microspheres as a new carrier for colonic drug targeting: Development and optimization by factorial design.  |  Gadalla, HH., et al. 2016. Carbohydr Polym. 153: 526-534. PMID: 27561525
  7. Bioengineered II-VI semiconductor quantum dot-carboxymethylcellulose nanoconjugates as multifunctional fluorescent nanoprobes for bioimaging live cells.  |  Mansur, AAP., et al. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 189: 393-404. PMID: 28843194
  8. Polymeric precipitants for the crystallization of macromolecules.  |  Patel, S., et al. 1995. Biochem Biophys Res Commun. 207: 819-28. PMID: 7864877
  9. Intranasal administration of HIV-DNA vaccine formulated with a polymer, carboxymethylcellulose, augments mucosal antibody production and cell-mediated immune response.  |  Hamajima, K., et al. 1998. Clin Immunol Immunopathol. 88: 205-10. PMID: 9714699
  10. A dielectric study of a carboxymethylcellulose in aqueous solution  |  Lars-Göran Allgén, Siw Roswall. 1954. Journal of Polymer Science. 12: 229-236.
  11. Characterization of Super▐Absorbent Material Based on Carboxymethylcellulose Sodium Salt Prepared by Electron Beam Irradiation  |  El▐Rehim, H. A. Abd; Hegazy, El▐Sayed. A.; Diaa, D. A. 2006. Journal of Macromolecular Science. 43: 101-113.
  12. Effect of carboxymethylcellulose and pregelatinized corn starch on the quality of amaranthus spaghetti  |  S Chillo, J Laverse, PM Falcone. 2007. Journal of Food Engineering. 83: 492-500.
  13. Effect of soluble fibre (guar gum and carboxymethylcellulose) addition on technological, sensory and structural properties of durum wheat spaghetti  |  N Aravind, M Sissons, CM Fellows. 2012. Food Chemistry. 131: 893-900.
  14. Capillary breakup extensional rheometry of sodium carboxymethylcellulose solutions in water and propylene glycol/water mixtures  |  Sylwia Różańska, Karel Verbeke, Jacek Różański, Christian Clasen, Patrycja Wagner. 2019. Journal of polymer science. 57: 1537-1547.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Carboxymethylcellulose, Sodium Salt, 250 g

sc-278812
250 g
$65.00

Carboxymethylcellulose, Sodium Salt, 1 kg

sc-278812A
1 kg
$147.00

Carboxymethylcellulose, Sodium Salt, 5 kg

sc-278812B
5 kg
$683.00

Carboxymethylcellulose, Sodium Salt, 10 kg

sc-278812C
10 kg
$1265.00

What is the shelf life of carboxymethylcellulose CAS-No. Revision Date 9004-32-4 And what are the physical effects of the product over time. 

Asked by: PatrickG
Thank you for your question. It would be helpful if you could call us directly at 800-457-3801 ext.1, allowing for a more interactive discussion of this and other related questions.
Answered by: Blake J
Date published: 2022-10-31

What is the Mw and the degree of substitution of the material? Do you have more than one type of CMC? Regards, Or

Asked by: Or Cohen
Thank you for your question. sc-278812 is the only Carboxymethylcellulose product that we currently offer. The molecular weight of this product may vary from lot to lot. You can download a lot-specific certificate of analysis from the product page or contact our technical service to receive a certificate of the currently available lot.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06
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Rated 5 out of 5 by from Vinkl rkovVinkl rkov , L. et al. (PubMed 26090454) developed a novel layered film wound dressing containing ibuprofen based on partially substituted fibrous Carboxymethylcellulose, Sodium. Results showed that developed films had adequate mechanical and swelling properties and an advantageous acidic surface pH for wound application. -SCBT Publication Review
Date published: 2015-01-31
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Carboxymethylcellulose, Sodium Salt is rated 5.0 out of 5 by 1.
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