Date published: 2025-10-8

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Amygdalin (CAS 29883-15-6)

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Alternate Names:
D-Mandelonitrile-β-gentiobioside
Application:
Amygdalin is cyanide containing glycoside used to characterize a variety of enzymes
CAS Number:
29883-15-6
Purity:
≥97%
Molecular Weight:
457.43
Molecular Formula:
C20H27NO11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Amygdalin is a compound that has been the subject of research due to its potential to release hydrogen cyanide upon enzymatic hydrolysis. It is used in studies involving plant metabolism, as it is a component of certain fruit kernels and seeds, such as those from almonds, apricots, and peaches. Researchers are interested in the enzymatic pathways that plants use to synthesize and degrade amygdalin, which can offer insights into plant defense mechanisms and the evolution of chemical deterrents in seeds. In the field of analytical chemistry, amygdalin is used as a reference compound for developing detection and quantification methods in complex matrices, such as food products. Additionally, amygdalin′s role in plant biology is studied to understand its impact on herbivores and how it may influence ecological interactions between plants and other organisms.


Amygdalin (CAS 29883-15-6) References

  1. [Amygdalin - structure and clinical significance].  |  Zdrojewicz, Z., et al. 2015. Pol Merkur Lekarski. 38: 300-3. PMID: 26039028
  2. Amygdalin, quackery or cure?  |  Blaheta, RA., et al. 2016. Phytomedicine. 23: 367-76. PMID: 27002407
  3. Amygdalin from Apricot Kernels Induces Apoptosis and Causes Cell Cycle Arrest in Cancer Cells: An Updated Review.  |  Saleem, M., et al. 2018. Anticancer Agents Med Chem. 18: 1650-1655. PMID: 29308747
  4. Can Amygdalin Provide any Benefit in Integrative Anticancer Treatment?  |  Třísková, A. and Rudá-Kučerová, J. 2019. Klin Onkol. 32: 360-366. PMID: 31610669
  5. Amygdalin - A pharmacological and toxicological review.  |  He, XY., et al. 2020. J Ethnopharmacol. 254: 112717. PMID: 32114166
  6. Amygdalin Decreases Adhesion and Migration of MDA-MB-231 and MCF-7 Breast Cancer Cell Lines.  |  Mosayyebi, B., et al. 2021. Curr Mol Pharmacol. 14: 667-675. PMID: 32778045
  7. Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds.  |  Jaszczak-Wilke, E., et al. 2021. Molecules. 26: PMID: 33924691
  8. Amygdalin Attenuates Airway Epithelium Apoptosis, Inflammation, and Epithelial-Mesenchymal Transition through Restraining the TLR4/NF-κB Signaling Pathway on LPS-Treated BEAS-2B Bronchial Epithelial Cells.  |  Si, Z. and Zhang, B. 2021. Int Arch Allergy Immunol. 182: 997-1007. PMID: 34428767
  9. The Multiple Actions of Amygdalin on Cellular Processes with an Emphasis on Female Reproduction.  |  Kolesarova, A., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 34577581
  10. Amygdalin Ameliorates Liver Fibrosis through Inhibiting Activation of TGF-β/Smad Signaling.  |  Xiao, Z., et al. 2023. Chin J Integr Med. 29: 316-324. PMID: 34816365
  11. Amygdalin as a chemoprotective agent in co-treatment with cisplatin.  |  Christodoulou, P., et al. 2022. Front Pharmacol. 13: 1013692. PMID: 36204233
  12. Amygdalin: A Review on Its Characteristics, Antioxidant Potential, Gastrointestinal Microbiota Intervention, Anticancer Therapeutic and Mechanisms, Toxicity, and Encapsulation.  |  Barakat, H., et al. 2022. Biomolecules. 12: PMID: 36291723
  13. Onco-immunity and therapeutic application of amygdalin: A review.  |  Alwan, AM., et al. 2023. J Oral Biol Craniofac Res. 13: 155-163. PMID: 36618007

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Amygdalin, 1 g

sc-257087
1 g
$91.00

Amygdalin, 5 g

sc-257087A
5 g
$272.00