Date published: 2025-10-18

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α-Zingiberene (CAS 495-60-3)

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Alternate Names:
(5R)-5-[(1S)-1,5-Dimethyl-4-hexen-1-yl]-2-methyl-1,3-cyclohexadiene
CAS Number:
495-60-3
Molecular Weight:
204.35
Molecular Formula:
C15H24
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Zingiberene is a natural compound found in the essential oils of ginger, cardamom, and other plants. It is a bicyclic sesquiterpene with anti-inflammatory, antioxidant, antimicrobial, and antifungal properties. Extensive scientific research has focused on α-Zingiberene to examine the effects of essential oils. Studies have also investigated the effects of this compound on diverse diseases like cancer, diabetes, and Alzheimer′s disease. Furthermore, Zingiberene has drawn interest as a potential food additive and preservative.


α-Zingiberene (CAS 495-60-3) References

  1. Zingiberene and curcumene in wild tomato.  |  Antonious, GF. and Kochhar, TS. 2003. J Environ Sci Health B. 38: 489-500. PMID: 12856930
  2. Overexpression of the lemon basil alpha-zingiberene synthase gene increases both mono- and sesquiterpene contents in tomato fruit.  |  Davidovich-Rikanati, R., et al. 2008. Plant J. 56: 228-238. PMID: 18643974
  3. Cytotoxicity Evaluation of Essential Oil and its Component from Zingiber officinale Roscoe.  |  Lee, Y. 2016. Toxicol Res. 32: 225-30. PMID: 27437089
  4. Variations in the Volatile Compositions of Curcuma Species.  |  Dosoky, NS., et al. 2019. Foods. 8: PMID: 30717336
  5. Variation in essential oil components and anti-inflammatory activity of Allophylus edulis leaves collected in central-western Brazil.  |  Santos, SMD., et al. 2021. J Ethnopharmacol. 267: 113495. PMID: 33091493
  6. Genetically Engineered Oleaginous Yeast Lipomyces starkeyi for Sesquiterpene α-Zingiberene Production.  |  Dai, Z., et al. 2021. ACS Synth Biol. 10: 1000-1008. PMID: 33915043
  7. α-zingiberene, a sesquiterpene from essential oil from leaves of Casearia sylvestris, suppresses inflammatory angiogenesis and stimulates collagen deposition in subcutaneous implants in mice.  |  Ferreira, BA., et al. 2022. Nat Prod Res. 36: 5858-5862. PMID: 34961386
  8. Chemical composition, antioxidant, and antimicrobial activity of Elsholtzia beddomei C. B. Clarke ex Hook. f. essential oil.  |  Sripahco, T., et al. 2022. Sci Rep. 12: 2225. PMID: 35140337
  9. Phytochemicals Profiling, Antimicrobial Activity and Mechanism of Action of Essential Oil Extracted from Ginger (Zingiber officinale Roscoe cv. Bentong) against Burkholderia glumae Causative Agent of Bacterial Panicle Blight Disease of Rice.  |  Gunasena, MT., et al. 2022. Plants (Basel). 11: PMID: 35684239
  10. Analysis of Volatile Constituents in Curcuma Species, viz. C. aeruginosa, C. zedoaria, and C. longa, from Nepal.  |  Poudel, DK., et al. 2022. Plants (Basel). 11: PMID: 35893636
  11. Chemical Composition, Antiaging Activities and Molecular Docking Studies of Essential Oils from Acca sellowiana (Feijoa).  |  El-Nashar, HAS., et al. 2022. Chem Biodivers. 19: e202200272. PMID: 35938449
  12. Prevention of Aflatoxin Occurrence Using Nuts-Edible Coating of Ginger Oil Nanoemulsions and Investigate the Molecular Docking Strategy.  |  Farouk, A., et al. 2022. Plants (Basel). 11: PMID: 36079610
  13. Ginger and parsley essential oils: chemical composition, antimicrobial activity, and evaluation of their application in cheese preservation.  |  Vitalini, S., et al. 2022. Nat Prod Res. 1-6. PMID: 36134545
  14. Essential Oil and Non-Volatile Metabolites from Kaunia longipetiolata (Sch.Bip. ex Rusby) R. M. King and H. Rob., an Andean Plant Native to Southern Ecuador.  |  Malagón, O., et al. 2022. Plants (Basel). 11: PMID: 36365423

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Zingiberene, 0.5 mg

sc-476197
0.5 mg
$357.00

α-Zingiberene, 5 mg

sc-476197A
5 mg
$2458.00