Date published: 2025-12-5

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α-Ionone (CAS 127-41-3)

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CAS Number:
127-41-3
Purity:
≥90%
Molecular Weight:
192.30
Molecular Formula:
C13H20O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Ionone is a liquid that ranges in color from yellow to amber. It has limited solubility in water but dissolves well in organic solvents. This fragrant compound is a breakdown product of carotenoids, created by enzymes known as carotenoid cleavage dioxygenases (CCD).


α-Ionone (CAS 127-41-3) References

  1. The Importance of the 5-Alkyl Substituent for the Violet Smell of Ionones: Synthesis of Racemic 5-Demethyl-α-ionone.  |  Chierici, S., et al. 2015. Nat Prod Commun. 10: 847-52. PMID: 26197497
  2. RIFM fragrance ingredient safety assessment, α-Ionone, CAS Registry Number 127-41-3.  |  Api, AM., et al. 2016. Food Chem Toxicol. 97S: S1-S10. PMID: 26702988
  3. Quantitative determination of α-ionone, β-ionone, and β-damascenone and enantiodifferentiation of α-ionone in wine for authenticity control using multidimensional gas chromatography with tandem mass spectrometric detection.  |  Langen, J., et al. 2016. Anal Bioanal Chem. 408: 6483-96. PMID: 27417694
  4. α-Ionone attenuates high-fat diet-induced skeletal muscle wasting in mice via activation of cAMP signaling.  |  Tong, T., et al. 2019. Food Funct. 10: 1167-1178. PMID: 30734800
  5. α-Ionone Protects Against UVB-Induced Photoaging in Human Dermal Fibroblasts.  |  Tong, T., et al. 2019. Molecules. 24: PMID: 31075987
  6. Integrating Enzyme and Metabolic Engineering Tools for Enhanced α-Ionone Production.  |  Chen, X., et al. 2019. J Agric Food Chem. 67: 13451-13459. PMID: 31079451
  7. α-Ionone, an Apocarotenoid, Induces Plant Resistance to Western Flower Thrips, Frankliniella occidentalis, Independently of Jasmonic Acid.  |  Murata, M., et al. 2019. Molecules. 25: PMID: 31861560
  8. Identification of α-ionone, nootkatone, and their derivatives as TGR5 agonists.  |  Sasaki, T., et al. 2023. Biochem Biophys Res Commun. 653: 147-152. PMID: 36870239
  9. α-Ionone protects against UVB-induced photoaging in epidermal keratinocytes.  |  Geng, R., et al. 2023. Chin Herb Med. 15: 132-138. PMID: 36875429
  10. A Concise Diastereoselective Total Synthesis of α-Ambrinol.  |  López-Martínez, JL., et al. 2023. Mar Drugs. 21: PMID: 37103369
  11. α-ionone promotes keratinocyte functions and accelerates epidermal barrier recovery.  |  Yang, D., et al. 2023. Ann Transl Med. 11: 297. PMID: 37181335
  12. Dynamic change of the carotenoid metabolic pathway profile during oolong tea processing with supplementary LED light.  |  Ni, Z., et al. 2023. Food Res Int. 169: 112839. PMID: 37254414
  13. The characteristic of the key aroma-active components in white tea using GC-TOF-MS and GC-olfactometry combined with sensory-directed flavor analysis.  |  Ma, L., et al. 2023. J Sci Food Agric.. PMID: 37337850

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Ionone, 100 g

sc-239157
100 g
$75.00