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Allyl isothiocyanate (CAS 57-06-7)

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Alternate Names:
AITC; Oil of mustard
Application:
Allyl isothiocyanate is a compound which induces phase II detoxification enzymes in urinary bladder
CAS Number:
57-06-7
Purity:
≥95%
Molecular Weight:
99.15
Molecular Formula:
C4H5NS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Allyl isothiocyanate is a compound that functions as a potent antimicrobial agent in experimental applications. Its mechanism of action involves disrupting the cell membrane of microorganisms, leading to leakage of cellular contents and ultimately cell death. This compound targets the sulfur-containing amino acids and enzymes in the microbial cells, leading to the inhibition of essential cellular processes. Allyl isothiocyanate may exhibit strong antimicrobial activity against a wide range of bacteria, fungi, and other microorganisms. Its ability to disrupt microbial cell membranes makes it useful for studying the mechanisms of antimicrobial action and for developing potential applications where preservation is required. Allyl isothiocyanate is utilized for its ability to effectively inhibit the growth and proliferation of various microorganisms, making it a useful compound for investigating antimicrobial strategies and developing new approaches for controlling microbial contamination.


Allyl isothiocyanate (CAS 57-06-7) References

  1. Allyl Isothiocyanate Ameliorates Obesity by Inhibiting Galectin-12.  |  Lo, CW., et al. 2018. Mol Nutr Food Res. 62: e1700616. PMID: 29345776
  2. Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways.  |  Li, CX., et al. 2019. World J Gastroenterol. 25: 5120-5133. PMID: 31558861
  3. Allyl isothiocyanate upregulates MRP1 expression through Notch1 signaling in human bronchial epithelial cells.  |  Li, NN., et al. 2020. Can J Physiol Pharmacol. 98: 324-331. PMID: 31747319
  4. Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA1.  |  Oguri, G., et al. 2021. Heliyon. 7: e05816. PMID: 33458442
  5. Allyl isothiocyanate increases MRP1 expression in cigarette smoke extract-stimulated human bronchial epithelial cells via the JNK/Nrf2 pathway.  |  Zhang, M., et al. 2021. Exp Ther Med. 21: 409. PMID: 33692840
  6. Allyl Isothiocyanate: A TAS2R38 Receptor-Dependent Immune Modulator at the Interface Between Personalized Medicine and Nutrition.  |  Tran, HTT., et al. 2021. Front Immunol. 12: 669005. PMID: 33968075
  7. Allyl isothiocyanate attenuates LED light-induced retinal damage in rats: exploration for the potential molecular mechanisms.  |  Orhan, C., et al. 2021. Cutan Ocul Toxicol. 40: 376-386. PMID: 34493133
  8. Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity.  |  Waz, S. and Matouk, AI. 2022. Toxicol Mech Methods. 32: 194-203. PMID: 34635025
  9. Allyl Isothiocyanate in the Volatiles of Brassica juncea Inhibits the Growth of Root Rot Pathogens of Panax notoginseng by Inducing the Accumulation of ROS.  |  Liu, H., et al. 2021. J Agric Food Chem. 69: 13713-13723. PMID: 34780155
  10. The degradation of allyl isothiocyanate and its impact on methane production from anaerobic co-digestion of kitchen waste and waste activated sludge.  |  Qin, Y., et al. 2022. Bioresour Technol. 347: 126366. PMID: 34838636
  11. Comparative Effects of Sulforaphane and Allyl Isothiocyanate on 3T3-L1 Adipogenesis.  |  Sakuma, S., et al. 2022. J Nutr Metab. 2022: 8705163. PMID: 35096424
  12. Protective Effect of Allyl Isothiocyanate in an Experimentally Induced Rat Model for Dry Eye Syndrome.  |  Muz, OE., et al. 2022. Curr Eye Res. 47: 704-714. PMID: 35176939
  13. Effects of Allyl Isothiocyanate on Oxidative and Inflammatory Stress in Type 2 Diabetic Rats.  |  Okulicz, M., et al. 2022. Molecules. 27: PMID: 36080332
  14. Allyl Isothiocyanate (AITC) Induces Apoptotic Cell Death In Vitro and Exhibits Anti-Tumor Activity in a Human Glioblastoma GBM8401/luc2 Model.  |  Lu, KW., et al. 2022. Int J Mol Sci. 23: PMID: 36142326

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Allyl isothiocyanate, 5 g

sc-252361
5 g
$43.00
US: Only available in the US

Allyl isothiocyanate, 100 g

sc-252361A
100 g
$66.00
US: Only available in the US

Allyl isothiocyanate, 500 g

sc-252361B
500 g
$117.00
US: Only available in the US

AITCのペーハーはいくらですか?ガス化したAITCに和紙が暴露されると劣化しますか?以上。

Asked by: サシガメ55
Thank you for your question. Please contact our Technical Service Department for more information on this question. Our Asian Technical Service team is available at (+86) 021-60936350 or asia@scbio.cn or by live chat on our website.
Answered by: Technical Support 15
Date published: 2019-12-04
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Rated 5 out of 5 by from Ling X; et alLing X; et al. (PubMed ID: 26396928) determined that Allyl isothiocyanate enhances the activity of cisplatin in vivo and in vitro. -SCBT Publication Review
Date published: 2015-05-21
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Allyl isothiocyanate | CAS 57-06-7 is rated 5.0 out of 5 by 1.
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