Date published: 2026-4-19

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Alitame (CAS 80863-62-3)

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Alternate Names:
L-α-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide
Application:
Alitame is A dipeptide amide derivative of aspartic acid
CAS Number:
80863-62-3
Purity:
≥95%
Molecular Weight:
331.43
Molecular Formula:
C14H25N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Alitame is a dipeptide amide derivative of aspartic acid (sc-257393). Alitame possesses a sweetness approximately ten times greater than that of Aspartame. Furthermore, it exhibits a longer half-life compared to Aspartame. Considered a relatively neutral compound, Alitame is practically insoluble in water. It predominantly resides in the cytoplasm within cells.


Alitame (CAS 80863-62-3) References

  1. Responses of single taste fibers and whole chorda tympani and glossopharyngeal nerve in the domestic pig, Sus scrofa.  |  Danilova, V., et al. 1999. Chem Senses. 24: 301-16. PMID: 10400449
  2. The intake of intense sweeteners - an update review.  |  Renwick, AG. 2006. Food Addit Contam. 23: 327-38. PMID: 16546879
  3. [Simultaneous determination of neotame, alitame and aspartame in foods by HPLC].  |  Matsumoto, H., et al. 2008. Shokuhin Eiseigaku Zasshi. 49: 31-6. PMID: 18344656
  4. Simultaneous determination of nonnutritive sweeteners in foods by HPLC/ESI-MS.  |  Yang, DJ. and Chen, B. 2009. J Agric Food Chem. 57: 3022-7. PMID: 19275236
  5. Retention behaviour of some high-intensity sweeteners on different SPE sorbents.  |  Zygler, A., et al. 2010. Talanta. 82: 1742-8. PMID: 20875571
  6. The content of high-intensity sweeteners in different categories of foods available on the Polish market.  |  Zygler, A., et al. 2012. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 29: 1391-401. PMID: 22827164
  7. [Simultaneous determination of aspartame and alitame in jellies and preserved fruits by HPLC].  |  Jiang, D., et al. 2012. Wei Sheng Yan Jiu. 41: 467-70, 475. PMID: 23050451
  8. The role of artificial and natural sweeteners in reducing the consumption of table sugar: A narrative review.  |  Mooradian, AD., et al. 2017. Clin Nutr ESPEN. 18: 1-8. PMID: 29132732
  9. [Simultaneous determination of nine artificial sweeteners in food by solid-phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry].  |  Tang, J., et al. 2019. Se Pu. 37: 619-625. PMID: 31152512
  10. Quantification of artificial sweeteners in alcoholic drinks using direct analysis in real-time QTRAP mass spectrometry.  |  Li, X., et al. 2021. Food Chem. 342: 128331. PMID: 33097326
  11. The sensory properties and metabolic impact of natural and synthetic sweeteners.  |  Mora, MR. and Dando, R. 2021. Compr Rev Food Sci Food Saf. 20: 1554-1583. PMID: 33580569
  12. Taste responsiveness of chimpanzees (Pan troglodytes) and black-handed spider monkeys (Ateles geoffroyi) to eight substances tasting sweet to humans.  |  Pereira, S., et al. 2021. Physiol Behav. 238: 113470. PMID: 34048820
  13. Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae.  |  Saputra, F., et al. 2021. Biology (Basel). 10: PMID: 34207293
  14. An updated multifaceted overview of sweet proteins and dipeptides as sugar substitutes; the chemistry, health benefits, gut interactions, and safety.  |  Farag, MA., et al. 2022. Food Res Int. 162: 111853. PMID: 36461268
  15. Adaptation of sweeteners in water and in tannic acid solutions.  |  Schiffman, SS., et al. 1994. Physiol Behav. 55: 547-59. PMID: 8190776

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Alitame, 1 g

sc-396439
1 g
$490.00

Alitame, 5 g

sc-396439A
5 g
$1428.00