Molecular structure of Adrenochrome, CAS Number: 54-06-8
Adrenochrome (CAS 54-06-8)
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Alternate Names:
3-Hydroxy-1-methyl-5,6-indolinedione; 2,3-dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione
Application:
Adrenochrome is an inhibitor of catechol-o-methyltransferase
CAS Number:
54-06-8
Molecular Weight:
179.17
Molecular Formula:
C9H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adrenochrome is an oxidation product of adrenaline (ephinephrine, norepinephrine). It inhibits COMT (Catechol-O-methyltransferase), promotes the synthesis of prostaglandins in brain tissue in vitro, promotes the secretion of nerve growth factor by L-M ce.
Adrenochrome (CAS 54-06-8) References
- Oxidation process of adrenaline in freshly isolated rat cardiomyocytes: formation of adrenochrome, quinoproteins, and GSH adduct. | Costa, VM., et al. 2007. Chem Res Toxicol. 20: 1183-91. PMID: 17630707
- Neonatal exposure to estradiol valerate programs ovarian sympathetic innervation and follicular development in the adult rat. | Sotomayor-Zárate, R., et al. 2008. Biol Reprod. 78: 673-80. PMID: 18077802
- Neuroprotective Properties of Quinone Reductase 2 Inhibitor M-11, a 2-Mercaptobenzimidazole Derivative. | Voronin, MV., et al. 2021. Int J Mol Sci. 22: PMID: 34884863
- Anti-Obesity Actions of Two Separated Aqueous Extracts From Arbutus (Arbutus unedo) and Hawthorn (Crataegus monogyna) Fruits Against High-Fat Diet in Rats via Potent Antioxidant Target. | Wahabi, S., et al. 2023. Dose Response. 21: 15593258231179904. PMID: 37275393
- Effect of neonatal melatonin administration on behavioral and brain electrophysiological and redox imbalance in rats. | Araújo, AO., et al. 2023. Front Neurosci. 17: 1269609. PMID: 37901423
- Prophylactic Coloprotective Effect of Urtica dioica Leaves against Dextran Sulfate Sodium (DSS)-Induced Ulcerative Colitis in Rats. | Dakhli, N., et al. 2023. Medicina (Kaunas). 59: PMID: 38004039
- Regulatory effect of bacterial melanin on the isoforms of new superoxide-producing associates from rat tissues in rotenone-induced Parkinson's disease. | Danielyan, M., et al. 2023. BMC Neurosci. 24: 69. PMID: 38124101
- Sex-dependent effect of sublethal copper concentrations on de novo cholesterol synthesis in astrocytes and their possible links to variations in cholesterol and amyloid precursor protein levels in neuronal membranes. | Zubillaga, M., et al. 2024. Biol Sex Differ. 15: 4. PMID: 38191520
- Methanol Crude Peel Extract of P. granatum Prevents Oxidative Damage in Kidneys of Rats Exposed to Highly Active Antiretroviral Therapy. | Kwizera, E., et al. 2024. J Exp Pharmacol. 16: 1-11. PMID: 38213945
- Phytochemical Properties of Crataegus azarolus Berries Decoction Extract and Evaluation of its Protective Activity Against Acetic Acid-Induced Ulcerative Colitis in Rats. | Sammari, H., et al. 2024. Dose Response. 22: 15593258241226890. PMID: 38223297
- 24-Epibrassinolide Reduces Drought-Induced Oxidative Stress by Modulating the Antioxidant System and Respiration in Wheat Seedlings. | Avalbaev, A., et al. 2024. Plants (Basel). 13: PMID: 38256702
- Neuroprotective potential of Afzelin: A novel approach for alleviating catalepsy and modulating Bcl-2 expression in Parkinson's disease therapy. | Alharthy, KM., et al. 2024. Saudi Pharm J. 32: 101928. PMID: 38261905
- Detection of epinephrine using a K2Fe4O7 modified glassy carbon electrode. | Jiang, M., et al. 2024. RSC Adv. 14: 15408-15412. PMID: 38741971
Inhibitor of:
COMT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adrenochrome, 25 mg | sc-206029 | 25 mg | $120.00 | |||
Adrenochrome, 250 mg | sc-206029A | 250 mg | $480.00 |