3-Hydroxyanthranilic acid A tryptophan metabolite along the kynurenine pathway

3-Hydroxyanthranilic acid (CAS 548-93-6)

3-Hydroxyanthranilic acid | CAS 548-93-6 is rated 5.0 out of 5 by 1.
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Synonym: 2-Amino-3-hydroxybenzoic acid
Application: A tryptophan metabolite along the kynurenine pathway
CAS Number: 548-93-6
Purity: ≥95%
Molecular Weight: 153.14
Molecular Formula: C7H7NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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3-Hydroxyanthranilic acid is a tryptophan metabolite along the kynurenine pathway. 3-Hydroxyanthranilic acid has been shown to induce apoptosis in T cells.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in 1N HCl (10 mg/ml), water (partly), ether, chloroform, and alcohols.
Storage :
Store at room temperature
Melting Point :
240° C (lit.)(dec.)
Boiling Point :
~356.9° C at 760 mmHg (Predicted)
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: IC50 = 1.44 µM (Plasmodium berghei); Protein RecA: EC5050 = 5.43 µM (Mycobacterium tuberculosis); G6PD: IC50 = 24 µM (human)
pK Values :
pKa: 2.08 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
DG2625000
PubChem CID :
86
MDL Number :
MFCD00007700
EC Number :
208-962-5
Beilstein Registry :
0973356
SMILES :
C1=CC(=C(C(=C1)O)N)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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2 questions: 1. What is the appearance of your product (3-HAA)(color). 2. What is the solubility, what is the choice of solvents. Thank you

Asked by: dsagher
Thank you for your question. 3-Hydroxyanthranilic acid (CAS 548-93-6) has the appearance of a Light Pink to Light Brown Solid. Soluble in 1N HCl (10 mg/ml), water (partly), ether, chloroform, and alcohols.
Answered by: Technical Support
Date published: 2017-02-04
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Rated 5 out of 5 by from Reyes Reyes-Ocampo J; et al. (PubMed ID: 26254737) determined that 3-Hydroxyanthranilic acid increased cytotoxicity in rat cultured cortical astrocytes and induced circling behavior and morphological changes of injected animals. -SCBT Publication Review
Date published: 2015-06-10
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