Date published: 2025-10-3

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2-Nitrobenzaldehyde (CAS 552-89-6)

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Application:
2-Nitrobenzaldehyde is a potential starting material for synthesis
CAS Number:
552-89-6
Purity:
≥95%
Molecular Weight:
151.12
Molecular Formula:
C7H5NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Nitrobenzaldehyde (2-NBA) is a versatile synthetic organic compound. This colorless solid possesses a pungent odor and exhibits a melting point range of 38-40° C. Due to its high reactivity, 2-Nitrobenzaldehyde finds utility as a valuable reagent in numerous chemical reactions. It is also recognized by alternative names such as 2-nitrobenzene aldehyde, 2-nitrobenzene-1-carbaldehyde, and 2-nitrophenylaldehyde. In the realm of scientific research, 2-Nitrobenzaldehyde finds diverse applications. It serves as a reagent in various chemical reactions and can act as a probe to investigate the structure and function of proteins and other biomolecules. Additionally, 2-Nitrobenzaldehyde exerts a broad range of effects on cells and proteins. It can function as an oxidant, reducing agent, and chelating agent. Furthermore, it interacts with proteins, forming covalent adducts that have the potential to modulate the structure and function of these important biomolecules.


2-Nitrobenzaldehyde (CAS 552-89-6) References

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  2. Hydrogen-bonded dimers in 2-nitrobenzaldehyde hydrazone and a three-dimensional hydrogen-bonded framework in 3-nitrobenzaldehyde hydrazone.  |  Glidewell, C., et al. 2004. Acta Crystallogr C. 60: o686-9. PMID: 15345857
  3. Effects of 4,5-dimethoxy groups on the time-resolved photoconversion of 2-nitrobenzyl alcohols and 2-nitrobenzaldehyde into nitroso derivatives.  |  Görner, H. 2005. Photochem Photobiol Sci. 4: 822-8. PMID: 16189558
  4. Improved gas chromatographic method for determination of daminozide by alkaline hydrolysis and 2-nitrobenzaldehyde derivatization and survey results of daminozide in agricultural products.  |  Steinbrecher, K., et al. 1990. J Assoc Off Anal Chem. 73: 512-5. PMID: 2211471
  5. Synthesis, characterization and biological activity of transition metal complexes with Schiff bases derived from 2-nitrobenzaldehyde with glycine and methionine.  |  Singh, BK., et al. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 94: 143-51. PMID: 22522296
  6. Cloning, expression, purification, and characterization of a novel single-chain variable fragment antibody against the 2-nitrobenzaldehyde derivative of a furaltadone metabolite in Escherichia coli.  |  Yang, W., et al. 2012. Protein Expr Purif. 84: 140-6. PMID: 22609338
  7. Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling.  |  Swietach, P., et al. 2013. Proc Natl Acad Sci U S A. 110: E2064-73. PMID: 23676270
  8. Synthesis and Antibacterial Evaluation of New Thione Substituted 1,2,4-Triazole Schiff Bases as Novel Antimicrobial Agents.  |  Akbari Dilmaghani, K., et al. 2015. Iran J Pharm Res. 14: 693-9. PMID: 26330857
  9. Design, Synthesis and Antibacterial Evaluation of Some New 2-Phenyl-quinoline-4-carboxylic Acid Derivatives.  |  Wang, X., et al. 2016. Molecules. 21: 340. PMID: 26978336
  10. Partially oxidized iridium clusters within dendrimers: size-controlled synthesis and selective hydrogenation of 2-nitrobenzaldehyde.  |  Higaki, T., et al. 2016. Nanoscale. 8: 11371-4. PMID: 27193739
  11. Suppressing Effect of 2-Nitrobenzaldehyde on Singlet Oxygen Generation, Fatty Acid Photooxidation, and Dye-Sensitizer Degradation.  |  Hajimohammadi, M., et al. 2018. Antioxidants (Basel). 7: PMID: 30567321
  12. The interaction of a thiosemicarbazone derived from R - (+) - limonene with lipid membranes.  |  Marquezin, CA., et al. 2021. Chem Phys Lipids. 234: 105018. PMID: 33232725
  13. Synthesis of Computationally Designed 2,5(6)-Benzimidazole Derivatives via Pd-Catalyzed Reactions for Potential E. coli DNA Gyrase B Inhibition.  |  Aroso, RT., et al. 2021. Molecules. 26: PMID: 33801316

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Nitrobenzaldehyde, 25 g

sc-256218
25 g
$49.00

2-Nitrobenzaldehyde, 100 g

sc-256218A
100 g
$102.00

2-Nitrobenzaldehyde, 500 g

sc-256218B
500 g
$398.00