2-Mesitylenesulfonyl chloride (CAS 773-64-8)

2-Mesitylenesulfonyl chloride is a reagent utilized in organic synthesis as a sulfonylating agent. It functions as an electrophile, reacting with nucleophiles such as alcohols, amines, and thiols to form sulfonate esters. 2-Mesitylenesulfonyl Chloride introduces the mesitylenesulfonyl (Mes) group into various organic compounds, allowing for the modification of their properties and reactivity. In the presence of a base, 2-Mesitylenesulfonyl chloride can undergo deprotonation to form the corresponding mesitylenesulfonyl anion, which can then participate in nucleophilic substitution reactions. Its mechanism of action involves the transfer of the mesitylenesulfonyl group to the target molecule, leading to the formation of a covalent bond between the sulfur atom of the sulfonyl chloride and the nucleophilic center of the substrate. 2-Mesitylenesulfonyl Chloride′s reactivity and selectivity make it useful for the synthesis of complex organic molecules and the modification of functional groups in a variety of research and development applications.