Date published: 2025-10-3

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2,5-Diformylfuran (CAS 823-82-5)

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Alternate Names:
2,5-Furandicarboxaldehyde; 2,5-Furandicarbaldehyde; 5-Formylfurfural; DFF
CAS Number:
823-82-5
Molecular Weight:
124.09
Molecular Formula:
C6H4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,5-Diformylfuran is derived from the oxidation of 5-hydroxymethyl furfural. It serves as a fundamental component in chemical synthesis. It functions as an organic building block, enabling the creation of various chemical compounds. Additionally, it acts as a precursor in the manufacturing process of valuable biopolymers.


2,5-Diformylfuran (CAS 823-82-5) References

  1. Selective Synthesis of 2,5-Diformylfuran by Sustainable 4-acetamido-TEMPO/Halogen-Mediated Electrooxidation of 5-Hydroxymethylfurfural.  |  Kashparova, VP., et al. 2016. Chem Asian J. 11: 2578-85. PMID: 27432749
  2. Superelectrophilic activation of 5-hydroxymethylfurfural and 2,5-diformylfuran: organic synthesis based on biomass-derived products.  |  Ryabukhin, DS., et al. 2016. Beilstein J Org Chem. 12: 2125-2135. PMID: 27829919
  3. Direct Transformation of HMF into 2,5-Diformylfuran and 2,5-Dihydroxymethylfuran without an External Oxidant or Reductant.  |  Li, G., et al. 2017. ChemSusChem. 10: 494-498. PMID: 27882693
  4. Oxidation of 5-Chloromethylfurfural (CMF) to 2,5-Diformylfuran (DFF).  |  Vicente, AI., et al. 2017. Molecules. 22: PMID: 28230746
  5. Fabrication of Trifunctional Polyoxometalate-Decorated Chitosan Nanofibers for Selective Production of 2,5-Diformylfuran.  |  Li, Y., et al. 2019. ChemSusChem. 12: 3515-3523. PMID: 31225716
  6. Metal Nitrate Catalysis for Selective Oxidation of 5-Hydroxymethylfurfural into 2,5-Diformylfuran under Oxygen Atmosphere.  |  Hong, M., et al. 2019. ACS Omega. 4: 7054-7060. PMID: 31459816
  7. Co-Immobilization of Tri-Enzymes for the Conversion of Hydroxymethylfurfural to 2,5-Diformylfuran.  |  Wu, Z., et al. 2019. Molecules. 24: PMID: 31658589
  8. Enzymatic conversion reactions of 5-hydroxymethylfurfural (HMF) to bio-based 2,5-diformylfuran (DFF) and 2,5-furandicarboxylic acid (FDCA) with air: mechanisms, pathways and synthesis selectivity.  |  Cajnko, MM., et al. 2020. Biotechnol Biofuels. 13: 66. PMID: 32308735
  9. Selective Oxidation of 5-Hydroxymethylfurfural to 2,5-Diformylfuran by Visible Light-Driven Photocatalysis over In Situ Substrate-Sensitized Titania.  |  Khan, A., et al. 2021. ChemSusChem. 14: 1351-1362. PMID: 33453092
  10. Aerobic oxidation of 5-hydroxymethylfurfural into 2,5-diformylfuran using manganese dioxide with different crystal structures: A comparative study.  |  Lin, KA., et al. 2021. J Colloid Interface Sci. 592: 416-429. PMID: 33691223
  11. High-efficiency synthesis of 5-hydroxymethylfurfural and 2,5-diformylfuran from fructose over magnetic separable catalysts.  |  Wei, W., et al. 2021. J Colloid Interface Sci. 602: 146-158. PMID: 34119754
  12. Selective Electrosynthesis of 2,5-Diformylfuran in a Continuous-Flow System.  |  Zhang, Y., et al. 2022. ChemSusChem. 15: e202102596. PMID: 34927792
  13. Cellulose-Derived Carbon Dot-Guided Growth of ZnIn2 S4 Nanosheets for Photocatalytic Oxidation of 5-Hydroxymethylfurfural into 2,5-Diformylfuran.  |  Qiu, J., et al. 2022. ChemSusChem. 15: e202200399. PMID: 35293693
  14. Highly efficient and tunable visible-light-catalytic synthesis of 2,5-diformylfuran using HBr and molecular oxygen.  |  Hu, W., et al. 2021. RSC Adv. 11: 23365-23373. PMID: 35479798
  15. MIL-47(V)-derived carbon-doped vanadium oxide for selective oxidation of 5-hydroxymethylfurfural to 2,5-diformylfuran.  |  Zhou, Y., et al. 2022. Dalton Trans. 51: 18473-18479. PMID: 36421021

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,5-Diformylfuran, 500 mg

sc-214015
500 mg
$312.00

2,5-Diformylfuran, 1 g

sc-214015A
1 g
$272.00

2,5-Diformylfuran, 5 g

sc-214015B
5 g
$502.00