Molecular structure of 15-Acetyl-Deoxynivalenol, CAS Number: 88337-96-6
15-Acetyl-Deoxynivalenol (CAS 88337-96-6)
Alternate Names:
15-Acetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one
Application:
15-Acetyl-Deoxynivalenol is a type B trichothecene mycotoxin
CAS Number:
88337-96-6
Molecular Weight:
338.35
Molecular Formula:
C17H22O7
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
15-Acetyl-Deoxynivalenol is a a type B trichothecene mycotoxin. Belonging to the deoxynivalenol family, 15-Acetyl-Deoxynivalenol has garnered significant attention in the realms of toxicology and food safety. Extensive studies have revealed its toxic nature, affecting various organisms, including humans and animals. Moreover, this mycotoxin has served as a valuable model compound for investigating the deleterious effects of other mycotoxins, further enhancing our understanding of their toxic mechanisms.
15-Acetyl-Deoxynivalenol (CAS 88337-96-6) References
- Multiplex PCR assay for the identification of nivalenol, 3- and 15-acetyl-deoxynivalenol chemotypes in Fusarium. | Quarta, A., et al. 2006. FEMS Microbiol Lett. 259: 7-13. PMID: 16684095
- Cloning, expression, and characterization of a single-domain antibody fragment with affinity for 15-acetyl-deoxynivalenol. | Doyle, PJ., et al. 2008. Mol Immunol. 45: 3703-13. PMID: 18632156
- Heat- and cold-shock responses in Fusarium graminearum 3 acetyl- and 15 acetyl-deoxynivalenol chemotypes. | Vujanovic, V., et al. 2012. J Microbiol. 50: 97-102. PMID: 22367943
- Inter-laboratory study of an LC-MS/MS method for simultaneous determination of deoxynivalenol and its acetylated derivatives, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in wheat. | Yoshinari, T., et al. 2013. Shokuhin Eiseigaku Zasshi. 54: 75-82. PMID: 23470877
- Natural occurrence of deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, nivalenol, 4,7-dideoxynivalenol, and zearalenone in polish wheat. | Perkowski, J., et al. 1990. Mycotoxin Res. 6: 7-12. PMID: 23605357
- Development and validation of an LC-MS/MS method for the toxicokinetic study of deoxynivalenol and its acetylated derivatives in chicken and pig plasma. | Broekaert, N., et al. 2014. J Chromatogr B Analyt Technol Biomed Life Sci. 971: 43-51. PMID: 25264912
- Cytotoxic effects and degradation products of three mycotoxins: alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in liver hepatocellular carcinoma cells. | Juan-García, A., et al. 2015. Toxicol Lett. 235: 8-16. PMID: 25772259
- Binary and tertiary combination of alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on HepG2 cells: Toxic effects and evaluation of degradation products. | Juan-García, A., et al. 2016. Toxicol In Vitro. 34: 264-273. PMID: 27131905
- Natural occurrence of deoxynivalenol, 15-acetyl-deoxynivalenol, and zearalenone in refusal factor corn stored since 1972. | Abbas, HK., et al. 1986. Appl Environ Microbiol. 51: 841-3. PMID: 2939798
- Natural occurrence and clastogenic effects of nivalenol, deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, and zearalenone in corn from a high-risk area of esophageal cancer. | Hsia, CC., et al. 1988. Cancer Detect Prev. 13: 79-86. PMID: 2977296
- Clinical impact of deoxynivalenol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on the severity of an experimental Mycoplasma hyopneumoniae infection in pigs. | Michiels, A., et al. 2018. BMC Vet Res. 14: 190. PMID: 29914486
- Effects of deoxynivalenol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on parameters associated with oxidative stress in HepG2 cells. | Juan-García, A., et al. 2019. Mycotoxin Res. 35: 197-205. PMID: 30806951
- Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis. | Yang, YX., et al. 2020. Toxicol In Vitro. 66: 104838. PMID: 32229167
- Validation of LC-MS/MS Coupled with a Chiral Column for the Determination of 3- or 15-Acetyl Deoxynivalenol Mycotoxins from Fusarium graminearum in Wheat. | Wang, L., et al. 2021. Toxins (Basel). 13: PMID: 34564663
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15-Acetyl-Deoxynivalenol, 1 mg | sc-213611 | 1 mg | $128.00 | |||
15-Acetyl-Deoxynivalenol, 5 mg | sc-213611A | 5 mg | $440.00 |