Date published: 2026-4-14

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12-Hydroxystearyl alcohol (CAS 2726-73-0)

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Alternate Names:
1,12-Octadecanediol
CAS Number:
2726-73-0
Purity:
≥99%
Molecular Weight:
286.49
Molecular Formula:
C18H38O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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12-Hydroxystearyl alcohol is a hydroxylated fatty alcohol, widely utilized in biochemical and materials science research. This compound features a hydroxyl group on the 12th carbon of the stearyl chain, which imparts unique physicochemical properties and biological activities. Researchers employ 12-Hydroxystearyl alcohol to investigate its role in lipid metabolism and its interactions with enzymes involved in the oxidation and reduction of fatty alcohols and fatty acids. It serves as a substrate for enzymes such as alcohol dehydrogenases and fatty acid synthases, providing insights into their catalytic mechanisms and substrate specificities. In material science, 12-Hydroxystearyl alcohol is used to synthesize novel polymers and surfactants. Its hydroxyl group allows for the formation of ester and ether linkages, making it a valuable building block for producing biocompatible and biodegradable materials. These materials have applications in various industries, including cosmetics, pharmaceuticals, and biodegradable plastics. The compound′s amphiphilic nature also makes it useful in studying the formation and stability of emulsions and micelles, contributing to the development of new formulations and delivery systems. Furthermore, 12-Hydroxystearyl alcohol is utilized in the study of lipid signaling pathways. Its incorporation into cellular models helps researchers explore how hydroxylated fatty alcohols influence membrane fluidity, lipid raft formation, and signaling processes. This research enhances the understanding of lipid-mediated cellular functions and the regulatory roles of fatty alcohols in biological systems. Overall, 12-Hydroxystearyl alcohol is a versatile compound that advances research in lipid biochemistry, enzymology, and material science, providing valuable insights into both fundamental and applied aspects of these fields.


12-Hydroxystearyl alcohol (CAS 2726-73-0) References

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  2. 12-Hydroxystearic acid lipid tubes under various experimental conditions.  |  Fameau, AL., et al. 2010. J Colloid Interface Sci. 341: 38-47. PMID: 19846108
  3. An apparatus and method for the coating of solid particles.  |  Robinson, MJ., et al. 1968. J Pharm Sci. 57: 1983-8. PMID: 5725934
  4. Castor oil-derived plasticizers. Some nitrogen-containing derivatives as plasticizers for vinyl chloride-vinyl acetate copolymer and cellulose acetate resins  |  Frank C. Magne, Harold P. Dupuy & Leo A. Goldblatt. 1959. Journal of the American Oil Chemists Society. 36: 635–637.
  5. Reduction of Fatty Acid Methyl Esters with Sodium Borohydride-t-Butanol-Methanol  |  Y. Rajeswara Rao, A. J. Pantulu, G. Lakshminarayana. 1987. Lipid/Fett,. 89: 398-400.
  6. Branched polyethylene mimicry by metathesis copolymerization of fatty acid-based α,ω-dienes  |  Thomas Lebarbé,abc Mehdi Neqal,ab Etienne Grau,ab Carine Alfosd and Henri Cramail*ab. 2014. Green Chem. 16: 1755-1758.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

12-Hydroxystearyl alcohol, 1 g

sc-213598
1 g
$180.00