Date published: 2026-7-12

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VHY Antibody (F-11): sc-393888

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Datasheets
  • VHY Antibody (F-11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 10-37 at the N-terminus of VHY of human origin
  • recommended for detection of VHY of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for VHY Antibody (F-11) for WB applications. These reagents are now offered in bundles with VHY Antibody (F-11) (see ordering information below).
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    VHY Antibody (F-11) is a mouse monoclonal IgG1 antibody that detects VHY in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-VHY antibody (F-11) specifically targets VH1-related member Y, a crucial player in the regulation of mitogen-activated protein (MAP) kinases, which are integral to various signal transduction pathways that respond to diverse stimuli and influence numerous physiological and pathological processes within cells. VHY monoclonal antibody (F-11) recognizes a protein significant for dephosphorylating critical phosphothreonine and phosphotyrosine residues in MAP kinases, thereby modulating their activity and ensuring proper cellular responses to growth factors and stress signals. VHY (F-11) antibody detects high expression in the testis, especially in pachytene spermatocytes and round spermatids, where VHY localizes to the plasma membrane, indicating potential involvement in spermatogenesis and cellular signaling during meiosis. VHY′s interaction with and regulation of MAP kinases underscores importance in maintaining cellular homeostasis and potential implications in reproductive biology and related disorders.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    VHY Antibody (F-11)

    sc-393888
    200 µg/ml
    $322.00

    VHY Antibody (F-11): m-IgG Fc BP-HRP Bundle

    sc-538331
    200 µg Ab; 10 µg BP
    $361.00

    VHY Antibody (F-11): m-IgGκ BP-HRP Bundle

    sc-535919
    200 µg Ab; 40 µg BP
    $361.00

    VHY Antibody (F-11): m-IgG1 BP-HRP Bundle

    sc-545647
    200 µg Ab; 20 µg BP
    $361.00

    VHY (F-11) Neutralizing Peptide

    sc-393888 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393888 P appropriate for?

    Asked by: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2026, m_7, d_11, h_12CST
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    Rated 5 out of 5 by from Great Western blot data of VHY expression in nonGreat Western blot data of VHY expression in non-transfected and human VHY transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-03-02
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    VHY Antibody (F-11) is rated 5.0 out of 5 by 1.
    • y_2026, m_7, d_11, h_12
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