UDP-GlcDH Anticorpo (D-2): sc-137005
- UDP-GlcDH Anticorpo D-2é um anticorpo monoclonal produzido em camundongo IgG2b (kappa light chain) fornecido em 200 µg/ml
- anti-aminioácidos 195-494 mapeamento no C-terminus de UDP-GlcDH de human origem
- recomendado para a detecção de UDP-glucose-6 dehydrogenase de mouse, rat e human origem em
- m-IgG2b BP-HRP e m-IgGκ BP-HRP são os reagentes de deteção secundários preferidos para UDP-GlcDH Anticorpo (D-2) para aplicações WB and IHC(P). Estes reagentes são agora oferecidos em conjuntos com UDP-GlcDH Anticorpo (D-2) (ver informações para encomenda abaixo).
LINKS RÁPIDOS
UDP-GlcDH (also called UDP-glucose 6-dehydrogenase, UGDH or UDPGDH) is a member of the UDP-glucose/GDP-mannose dehydrogenase family. UDP-GlcDH converts UDP-glucose to UDP-glucuronic acid, which is a crucial component in the biosynthesis of the glycosaminoglycans, hyaluronan, heparan sulfate and chondroitin sulfate. Found as common components of the extracellular matrix, these glycosaminoglycans are significant in signal transduction, cell migration, cancer growth and cancer metastasis. UDP-glucuronic acid (UDP-GlcA) is needed in the liver for the excretion of toxic compounds. UDP-GlcDH is a ubiquitously expressed protein most abundant in the liver. The protein structure of UDP-GlcDH was first analyzed in cow liver and found to be a homohexamer. This structure is well conserved between species and phyla with an overall 97% sequence identity shared between different species of mammals. Research indicates that UDP-GlcDH expression is upregulated by TGFβ and downregulated by hypoxia.
Informacoes sobre ordens
| Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
UDP-GlcDH Anticorpo (D-2) | sc-137005 | 200 µg/ml | $316.00 | |||
Pacote do UDP-GlcDH (D-2): m-IgGκ BP-HRP | sc-534640 | 200 µg Ab; 40 µg BP | $354.00 | |||
Pacote do UDP-GlcDH (D-2): m-IgG2b BP-HRP | sc-549274 | 200 µg Ab; 10 µg BP | $354.00 |