Tenascin-C Antibody (300-3): sc-13578
- Tenascin-C Antibody (300-3) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- raised against purified human Tenascin
- recommended for detection of Tenascin-C of human origin by WB, IP and IF
- See Tenascin-C (E-9): sc-25328 for Tenascin-C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Tenascin-C Antibody (300-3) for WB applications. These reagents are now offered in bundles with Tenascin-C Antibody (300-3) (see ordering information below).
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Tenascin-C Antibody (300-3) is a mouse monoclonal IgG1 antibody that detects Tenascin-C in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Tenascin-C is a crucial component of the extracellular matrix, playing a significant role in cell adhesion and migration, which are vital processes during embryonic development and tissue repair. Anti-Tenascin-C antibody (300-3) enables detection of this protein in various tissues undergoing active remodeling. The unique structure of Tenascin-C, characterized by fibronectin type III repeats, allows interaction with a variety of cell surface receptors, influencing cellular behavior and signaling pathways. Expression of Tenascin-C increases in response to injury, highlighting a role in tissue regenerative processes. Tenascin-C monoclonal antibody (300-3) helps researchers gain insights into tissue remodeling dynamics and pathological processes associated with various diseases, making this tool invaluable for studies in developmental biology and cancer research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Tenascin-C Antibody (300-3) References:
- Advances in tenascin-C biology. | Midwood, KS., et al. 2011. Cell Mol Life Sci. 68: 3175-99. PMID: 21818551
- Tenascin-C Signaling in melanoma. | Shao, H., et al. 2015. Cell Adh Migr. 9: 125-30. PMID: 25482624
- Tenascin-C and integrins in cancer. | Yoshida, T., et al. 2015. Cell Adh Migr. 9: 96-104. PMID: 25793576
- Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration. | Zhou, S., et al. 2020. Cell Res. 30: 1063-1077. PMID: 32839552
- Tenascin-C in Osteoarthritis and Rheumatoid Arthritis. | Hasegawa, M., et al. 2020. Front Immunol. 11: 577015. PMID: 33101302
- Tenascin-C in fibrosis in multiple organs: Translational implications. | Bhattacharyya, S., et al. 2022. Semin Cell Dev Biol. 128: 130-136. PMID: 35400564
- Tenascin-C is a driver of inflammation in the DSS model of colitis. | Ozanne, J., et al. 2022. Matrix Biol Plus. 14: 100112. PMID: 35669358
- A virological view of tenascin-C in infection. | Zuliani-Alvarez, L. and Piccinini, AM. 2023. Am J Physiol Cell Physiol. 324: C1-C9. PMID: 36458980
- Tenascin C in Lung Diseases. | Donovan, C., et al. 2023. Biology (Basel). 12: PMID: 36829478
- Tenascin-C targeting strategies in cancer. | Dhaouadi, S., et al. 2024. Matrix Biol. 130: 1-19. PMID: 38642843
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tenascin-C Antibody (300-3) | sc-13578 | 200 µg/ml | $322.00 | |||
Tenascin-C Antibody (300-3): m-IgG Fc BP-HRP Bundle | sc-536580 | 200 µg Ab; 10 µg BP | $361.00 | |||
Tenascin-C Antibody (300-3): m-IgGκ BP-HRP Bundle | sc-533731 | 200 µg Ab; 40 µg BP | $361.00 |