CD138/SDC1/Syndecan-1 Antibody (5G72): sc-73096
- CD138/SDC1/Syndecan-1 Antibody (5G72) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against U266 myeloma cell line of human origin
- recommended for detection of Syndecan-1 of mouse, rat and human origin by WB, IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD138/SDC1/Syndecan-1 (A-6): sc-390791 for CD138/SDC1/Syndecan-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD138/SDC1/Syndecan-1 Antibody (5G72). This work is in progress.
QUICK LINKS
SEE ALSO...
Syndecan-1 Antibody (5G72) is a mouse monoclonal IgG1 antibody that detects Syndecan-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Syndecan-1, also known as CD138, is a type I integral membrane proteoglycan that plays a crucial role in cell signaling and adhesion by serving as a receptor for the extracellular matrix. Syndecan-1 presence on the basolateral surfaces of epithelial cells, endothelial cells of sprouting capillaries, and embryonic condensing mesenchymal cells highlights its importance in tissue development and repair. Notably, Syndecan-1 interacts with various extracellular matrix components, including collagens, fibronectin, and thrombospondin, facilitating cellular communication and structural integrity. Additionally, Syndecan-1 has been shown to co-localize with actin-rich filaments, suggesting a role in linking the cytoskeleton to the extracellular matrix, which is vital for maintaining cell shape and motility. Anti-Syndecan-1 antibody (5G72) serves as an essential tool for researchers studying the dynamics of cell-matrix interactions and the implications of Syndecan-1 in various biological processes and diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD138/SDC1/Syndecan-1 Antibody (5G72) References:
- The role of syndecan-1 in cellular signaling and its effects on heparan sulfate biosynthesis in mesenchymal tumors. | Szatmári, T. and Dobra, K. 2013. Front Oncol. 3: 310. PMID: 24392351
- Syndecan-1 regulates the biological activities of interleukin-34. | Segaliny, AI., et al. 2015. Biochim Biophys Acta. 1853: 1010-21. PMID: 25662098
- Syndecan-1 in mechanosensing of nanotopological cues in engineered materials. | Le, V., et al. 2018. Biomaterials. 155: 13-24. PMID: 29156422
- Syndecan-1 Controls Lung Tumorigenesis by Regulating miRNAs Packaged in Exosomes. | Parimon, T., et al. 2018. Am J Pathol. 188: 1094-1103. PMID: 29355516
- Aberrant Expression of Syndecan-1 in Cervical Cancers. | Karászi, K., et al. 2020. Pathol Oncol Res. 26: 2255-2264. PMID: 32388727
- Expression of Syndecan-1 in Chronic Liver Diseases: Correlation With Hepatic Fibrosis. | Charchanti, A., et al. 2021. In Vivo. 35: 333-339. PMID: 33402482
- Serum syndecan-1 reflects organ dysfunction in critically ill patients. | Suzuki, K., et al. 2021. Sci Rep. 11: 8864. PMID: 33893369
- The role of actomyosin in the regulation of syndecan-1 in hyperosmosis. | Li, W. and Wang, W. 2021. Biochim Biophys Acta Gen Subj. 1865: 129975. PMID: 34343643
- Correlation between syndecan-1 level and PELOD-2 score and mortality in pediatric sepsis. | Pudjiadi, AH., et al. 2021. Rev Bras Ter Intensiva. 33: 549-556. PMID: 35081239
- Association of Preoperative and Postoperative Plasma Syndecan-1 and Colorectal Cancer Outcome. | Tanaka, H., et al. 2024. Anticancer Res. 44: 1611-1618. PMID: 38537984
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD138/SDC1/Syndecan-1 Antibody (5G72) | sc-73096 | 100 µg/ml | $322.00 | |||
CD138/SDC1/Syndecan-1 Antibody (5G72) FITC | sc-73096 FITC | 100 tests in 2 ml | $336.00 | |||
CD138/SDC1/Syndecan-1 Antibody (5G72) PE | sc-73096 PE | 100 tests in 2 ml | $349.00 |