Anti-Stat6 Anticorpo D-1é um anticorpo monoclonal produzido em camundongo IgG2b κ Stat6 anticorpo, citado em 19 publicações, fornecido em 200 µg/ml
específico para um epítopo mapeado entre os aminoácidos799-823 no C-terminus de Stat6 de mouse origem
Anti-Stat6 Anticorpo (D-1) é recomendado para a detecção de Stat6 de mouse, rat e human origem em WB, IP, IF, IHC(P) e ELISA
Anti-Stat6 Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
disponível como reagente TransCruz para ensaios de Gel Supershift e uso em ChIP (sc-374021 X, 200 µg/0.1 ml)
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de Stat6 (D-1): sc-374021.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for Stat6 Antibody (D-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with Stat6 Antibody (D-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
ChemCruz™ Produtos químicos
Stat Inibidores para análise funcional de respostas celulares a Stat
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Clique na imagem ou no botão para ampliar a imagem
Stat6 Antibody (D-1) is a high quality monoclonal Stat6 antibody (also designated IL-4 Stat antibody) suitable for the detection of the Stat6 protein of mouse, rat and human origin. Stat6 Antibody (D-1) is available as both the non-conjugated anti-Stat6 antibody form, as well as multiple conjugated forms of anti-Stat6 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of proteins that have been designated Stats (signal transducers and activators of transcription. The first members of this family to be described include Stat1α p91, Stat1β p84 (a form of p91 that lacks 38 COOH-terminal amino acids) and Stat2 p113. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Stat3, which becomes activated in response to epidermal growth factor (EGF) and interleukin-6 (IL-6), but not interferon-γ (IFN-γ) or Stat4, is an additional member of this family. It has been suggested that the phosphorylated forms of both Stat3 and Stat4 form homodimers as well as heterodimers with the other members of the Stat family, and that differential activation of different Stat proteins in response to different ligands should help to explain specificity in nuclear signaling from the cell surface. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Other members of the Stat family include Stat5, which has been shown to be activated by prolactin and by IL-3, and Stat6 (also designated IL-4 Stat), which is involved in IL-4-activated signaling pathways.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences