Saccharocarcin B CAS: 158475-33-3
MF: C68H103NO20
MW: 1254.6
An unusual tetronic acid with inhibitory effects on gram positive bacteria.

Saccharocarcin B (CAS 158475-33-3)

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Aplicação Saccharocarcin B is an unusual tetronic acid with inhibitory effects on gram positive bacteria
Numero VAT: 158475-33-3
Privada: >99%
Peso Molecular: 1254.6
Separar por Funcao: C68H103NO20
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
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Saccharocarcin B is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcins and versipelostatin which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway.

Estado físico :
Solid
Derivado de :
Amycolatopsis
envie :
Soluble in water (limitedly), ethanol, DMSO, methanol, and DMF.
Manutencao :
Store at -20° C
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
Numero de FAX :
MFCD14635442

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