RLA-DR Antibody (5K114): sc-71964

RLA-DR Antibody (5K114) is a mouse monoclonal IgG2b light chain antibody that detects the RLA-DR protein of rabbit origin by immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-RLA-DR antibody (5K114) is available in both non-conjugated and various conjugated forms, including phycoerythrin (PE). RLA-DR plays a crucial role in the immune response as a component of the major histocompatibility complex (MHC) class II molecules, which are essential for presenting antigens to CD4+ T cells. This interaction is vital for the activation of T cells and the subsequent orchestration of adaptive immune responses. RLA-DR is primarily located on the surface of antigen-presenting cells, such as B lymphocytes, dendritic cells, and macrophages, where RLA-DR (5K114) facilitates the recognition of foreign peptides. Understanding the expression and function of RLA-DR is important for elucidating mechanisms of immune regulation and for developing therapeutic strategies in immunological disorders. Notably, the rabbit genome contains several class II beta genes, including those for RLA-DR, which are co-expressed in B lymphocytes through the action of specific transcriptional factors, although the precise mechanisms remain to be fully elucidated.

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RLA-DR Antibody (5K114) References:

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