Molecular structure of Quercetagetin, CAS Number: 90-18-6
Quercetagetin (CAS 90-18-6)
See product citations (3)
Alternate Names:
6-Hydroxyquercetin
Application:
Quercetagetin is an ATP-competitive flavanol inhibitor of Pim-1 (PIM1) kinase
CAS Number:
90-18-6
Molecular Weight:
318.23
Molecular Formula:
C15H10O8
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A cell-permeable flavanol compound that acts a potent, ATP-competitive, and reversible inhibitor of PIM1 kinase (IC50 = 340 nM). Exhibits ≥7-fold selectivity over 8 other kinases tested, including PIM2 (IC50 = 3.45 µM), and little activity toward c-Abl even at concentrations as high as 200 µM. Inhibits cellular BAD phosphorylation (IC50 = 5.5 µM) and induces growth arrest (ED50 = 3.8 µM) in PIM1-expressing RWPE2 cells.
Quercetagetin (CAS 90-18-6) References
Holder, S., et al. 2007. Mol. Cancer Ther. 6, 163.Inhibitor of:
DDX57, Pim, and Pim-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Quercetagetin, 5 mg | sc-204221 | 5 mg | $333.00 |