Prolactin Antibody (PRL-151): sc-69875
- Prolactin Antibody (PRL-151) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against Prolactin of human origin
- recommended for detection of Prolactin of human origin by WB and IP
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Prolactin Antibody (PRL-151) for WB applications. This reagent is now offered in a bundle with Prolactin Antibody (PRL-151) (see ordering information below).
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Prolactin Antibody (PRL-151) is a mouse monoclonal IgG1 antibody that detects Prolactin in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Prolactin, a 226 amino acid protein, is primarily secreted by the anterior pituitary gland and plays a crucial role in various physiological processes, including lactation, reproduction, and immune regulation. Anti-Prolactin antibody (PRL-151) recognizes a protein involved in the development of mammary tissue and has been implicated in mammary cancer, where Prolactin acts as both a mitogen and a differentiating agent. Prolactin′s ability to enhance the proliferation of B cell hybridomas is significant, as this leads to increased antibody production, which is vital for effective immune responses. Prolactin has been shown to counteract the antiproliferative effects of the immunosuppressive cytokine TGF-beta, highlighting its importance in maintaining cellular growth and function. Prolactin′s association with autoimmune diseases, such as arthritis and type 1 diabetes, underscores its relevance in both health and disease, making Prolactin (PRL-151) antibody an essential tool for researchers studying these critical biological processes.
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Prolactin Antibody (PRL-151) References:
- Prolactin and prolactin-like polypeptides in rheumatoid arthritis. | Neidhart, M., et al. 1999. Biomed Pharmacother. 53: 218-22. PMID: 10424242
- Prolactin as a mitogen in mammary cells. | Das, R. and Vonderhaar, BK. 1997. J Mammary Gland Biol Neoplasia. 2: 29-39. PMID: 10887517
- Pituitary production of prolactin and prolactin-suppressing drugs. | Tansey, MJ. and Schlechte, JA. 2001. Lupus. 10: 660-4. PMID: 11721691
- Serum prolactin and migraine. | Masoud, SA. and Fakharian, E. 2005. Ann Saudi Med. 25: 489-91. PMID: 16438460
- The role of prolactin- and endometriosis-associated infertility. | Wang, H., et al. 2009. Obstet Gynecol Surv. 64: 542-7. PMID: 19624865
- Prolactin and pituitary tumors. | Silvestrini, F., et al. 1978. Curr Top Exp Endocrinol. 3: 131-72. PMID: 26521
- Prolactin transport into mouse brain is independent of prolactin receptor. | Brown, RS., et al. 2016. FASEB J. 30: 1002-10. PMID: 26567005
- Neuroleptics, prolactin, and osteoporosis. | Rogers, GA. and Burke, GV. 1987. Am J Psychiatry. 144: 388-9. PMID: 2881495
- Prolactin and migraine. | Murialdo, G. and Polleri, A. 1987. Headache. 27: 278-9. PMID: 3597085
- Prolactin responses to cimetidine. | Burland, WL., et al. 1979. Br J Clin Pharmacol. 7: 19-21. PMID: 760738
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prolactin Antibody (PRL-151) | sc-69875 | 200 µg/ml | $322.00 | |||
Prolactin Antibody (PRL-151): m-IgG Fc BP-HRP Bundle | sc-539252 | 200 µg Ab; 10 µg BP | $361.00 |