HSV-2 gG Envelope Protein Antibody (3D4): sc-56991

HSV-2 gG Envelope Protein Antibody (3D4) is a mouse monoclonal IgG1 antibody that detects HSV-2 gG Envelope Protein of Herpes Simplex Virus 2 origin by western blotting (WB) and immunofluorescence (IF). Anti-HSV-2 gG Envelope Protein antibody (3D4) is available as the non-conjugated format. HSV-2 gG Envelope Protein plays a crucial role in viral immune evasion, participating in host cell entry and latency establishment. HSV-2 gG Envelope Protein is located on the viral surface and mediates essential interactions with host cell receptors during infection. Glycoprotein G (gG) undergoes cleavage into a secreted amino-terminal portion and a heavily O-glycosylated carboxy-terminal portion, forming mature gG-2. Mature gG-2 functions as a type-specific antigen, making HSV-2 gG Envelope Protein a valuable target for HSV-2 infection serodiagnosis. Understanding HSV-2 gG Envelope Protein′s function and significance contributes to developing effective diagnostic tools and therapeutic strategies against herpes simplex virus infections.

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HSV-2 gG Envelope Protein Antibody (3D4) References:

1. Antibody responses to the herpes simplex virus type 2 glycoprotein G in sera of human immunodeficiency virus-infected patients in Slovakia.  |  Bystrická, M., et al. 1998. Acta Virol. 42: 319-24. PMID: 10358733
2. Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay.  |  Bystrická, M., et al. 1999. Acta Virol. 43: 399-402. PMID: 10825932
3. Conservation of type-specific B-cell epitopes of glycoprotein G in clinical herpes simplex virus type 2 isolates.  |  Liljeqvist, JA., et al. 2000. J Clin Microbiol. 38: 4517-22. PMID: 11101589
4. Seroreactive recombinant herpes simplex virus type 2-specific glycoprotein G.  |  Parkes, DL., et al. 1991. J Clin Microbiol. 29: 778-81. PMID: 1653787
5. Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2.  |  Bystrická, M., et al. 1991. Acta Virol. 35: 152-64. PMID: 1681713
6. Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection.  |  Bystrická, M., et al. 1997. Acta Virol. 41: 5-12. PMID: 9199708

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HSV-2 gG Envelope Protein Antibody (3D4) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HSV-2 gG Envelope Protein Antibody (3D4) Specifications

Alternate Product Name: HSV-2 gG Envelope Protein

Product Clone Name: 3D4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: HSV-2 gG Envelope Protein

Epitope Species: herpes simplex virus type 2

Product Reactivity/Detection: glycoprotein G Envelope Protein

Species Reactivity/Detection: Herpes Simplex Virus 2

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for HSV-2 gG Envelope Protein Antibody (3D4): N/A