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GTBP Antibody (E-8) is an IgG2a κ mouse monoclonal GTBP antibody that detects the GTBP protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. GTBP Antibody (E-8) is available as both the non-conjugated anti-GTBP antibody form, as well as multiple conjugated forms of anti-GTBP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is a MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
Alexa Fluor® é uma marca comercial da Molecular Probes Inc., OR., EUA
LI-COR® e Odyssey® são marcas registadas da LI-COR Biosciences
Informacoes sobre ordens
Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
GTBP Anticorpo (E-8) | sc-137015 | 200 µg/ml | $316.00 | |||
Pacote do GTBP (E-8): m-IgG Fc BP-HRP | sc-528837 | 200 µg Ab; 10 µg BP | $354.00 | |||
Pacote do GTBP (E-8): m-IgGκ BP-HRP | sc-521395 | 200 µg Ab, 40 µg BP | $354.00 | |||
Pacote do GTBP (E-8): m-IgG2a BP-HRP | sc-547181 | 200 µg Ab; 10 µg BP | $354.00 | |||
GTBP Anticorpo (E-8) AC | sc-137015 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GTBP Anticorpo (E-8) HRP | sc-137015 HRP | 200 µg/ml | $316.00 | |||
GTBP Anticorpo (E-8) FITC | sc-137015 FITC | 200 µg/ml | $330.00 | |||
GTBP Anticorpo (E-8) PE | sc-137015 PE | 200 µg/ml | $343.00 | |||
GTBP Anticorpo (E-8) Alexa Fluor® 488 | sc-137015 AF488 | 200 µg/ml | $357.00 | |||
GTBP Anticorpo (E-8) Alexa Fluor® 546 | sc-137015 AF546 | 200 µg/ml | $357.00 | |||
GTBP Anticorpo (E-8) Alexa Fluor® 594 | sc-137015 AF594 | 200 µg/ml | $357.00 | |||
GTBP Anticorpo (E-8) Alexa Fluor® 647 | sc-137015 AF647 | 200 µg/ml | $357.00 | |||
GTBP Anticorpo (E-8) Alexa Fluor® 680 | sc-137015 AF680 | 200 µg/ml | $357.00 | |||
GTBP Anticorpo (E-8) Alexa Fluor® 790 | sc-137015 AF790 | 200 µg/ml | $357.00 |