CPE Antibody (H-5): sc-393761
- CPE Antibody (H-5) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 171-199 near the N-terminus of CPE of mouse origin
- recommended for detection of precursor and mature CPE of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for CPE Antibody (H-5) for WB applications. These reagents are now offered in bundles with CPE Antibody (H-5) (see ordering information below).
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SEE ALSO...
CPE Antibody (H-5) is a mouse monoclonal IgG2a antibody that detects Carboxypeptidase E (CPE) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CPE plays a critical role in prohormone processing, specifically in the removal of C-terminal arginine or lysine residues following initial endoprotease cleavage, which is essential for the maturation of various peptide hormones. This enzymatic activity is particularly important in the processing of proinsulin, ensuring that insulin is produced in its active form, which is vital for glucose metabolism and overall energy homeostasis. Additionally, CPE is necessary for the proper development of photoreceptor synaptic terminals, facilitating normal signal transmission to the inner retina, thereby contributing to visual function. Anti-CPE antibody (H-5) provides reliable detection and characterization of CPE, making this tool invaluable for researchers studying hormonal regulation and retinal health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CPE Antibody (H-5) | sc-393761 | 200 µg/ml | $322.00 | |||
CPE Antibody (H-5): m-IgG Fc BP-HRP Bundle | sc-540908 | 200 µg Ab; 10 µg BP | $361.00 | |||
CPE Antibody (H-5): m-IgG2a BP-HRP Bundle | sc-546973 | 200 µg Ab; 10 µg BP | $361.00 | |||
CPE (H-5) Neutralizing Peptide | sc-393761 P | 100 µg/0.5 ml | $69.00 |