Date published: 2026-6-10

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Cholesterol (CAS 57-88-5)

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Alternate Names:
5-Cholesten-3beta-ol; Cholesterin
Application:
Cholesterol is a structural component of cell membranes
CAS Number:
57-88-5
Purity:
≥92%
Molecular Weight:
386.65
Molecular Formula:
C27H46O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. Cholesterol is suitable for use in liposome preparations.


Cholesterol (CAS 57-88-5) References

  1. Cholesterol, Alzheimer's disease, prion disorders: a ménage à trois?  |  Pani, A., et al. 2010. Curr Drug Targets. 11: 1018-31. PMID: 20450474
  2. Physiological and pathological implications of cholesterol.  |  Cortes, VA., et al. 2014. Front Biosci (Landmark Ed). 19: 416-28. PMID: 24389193
  3. On the puzzling distribution of cholesterol in the plasma membrane.  |  Giang, H. and Schick, M. 2016. Chem Phys Lipids. 199: 35-38. PMID: 26724709
  4. Common structural features of cholesterol binding sites in crystallized soluble proteins.  |  Bukiya, AN. and Dopico, AM. 2017. J Lipid Res. 58: 1044-1054. PMID: 28420706
  5. Measurement of Single-Molecule Forces in Cholesterol and Cyclodextrin Host-Guest Complexes.  |  Pandey, S., et al. 2021. J Phys Chem B. 125: 11112-11121. PMID: 34523939
  6. Site of Cholesterol Oxidation Impacts Its Localization and Domain Formation in the Neuronal Plasma Membrane.  |  Wilson, KA., et al. 2021. ACS Chem Neurosci. 12: 3873-3884. PMID: 34633798
  7. Synthesis and biological evaluation of cationic TopFluor cholesterol analogues.  |  Jurášek, M., et al. 2021. Bioorg Chem. 117: 105410. PMID: 34700109
  8. Cholesterol and glucose profiles according to different fasting C-peptide levels: a cross-sectional analysis in a healthy cohort from the Czech Republic.  |  Kron, V., et al. 2021. J Appl Biomed. 19: 220-227. PMID: 34907741
  9. Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.  |  Lin, DT., et al. 2022. J Nutr Biochem. 104: 108974. PMID: 35196576
  10. Effects of cholesterol on the mechanism of fengycin, a biofungicide.  |  Sur, S. and Grossfield, A. 2022. Biophys J. 121: 1963-1974. PMID: 35422413
  11. Effects of cholesterol and PIP2 on interactions between glycophorin A and Band 3 in lipid bilayers.  |  Qin, X., et al. 2022. Biophys J. 121: 2069-2077. PMID: 35524411
  12. The amount of membrane cholesterol required for robust cell adhesion and proliferation in serum-free condition.  |  Takii, S., et al. 2022. PLoS One. 17: e0259482. PMID: 35857759
  13. Absolute quantification of cholesterol from thin tissue sections by silver-assisted laser desorption ionization mass spectrometry imaging.  |  Nezhad, ZS., et al. 2022. Anal Bioanal Chem. 414: 6947-6954. PMID: 35953724

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cholesterol, 5 g

sc-202539C
5 g
$27.00

Cholesterol, 25 g

sc-202539
25 g
$88.00

Cholesterol, 100 g

sc-202539A
100 g
$129.00

Cholesterol, 250 g

sc-202539B
250 g
$210.00

Cholesterol, 1 kg

sc-202539D
1 kg
$583.00

Cholesterol, 5 kg

sc-202539E
5 kg
$2809.00