CAMK2A/CaMKII alpha Anticorpo (45): sc-136212
- CAMK2A/CaMKII alpha Anticorpo 45é um anticorpo monoclonal produzido em camundongo IgG1, citado em 1 publicações, fornecido em 50 µg/0.5 ml
- Produzido contra aminoácidos 448-460 de CaMKIIα de rat origem
- recomendado para a detecção de CaMKIIα de mouse, rat, human e canine origem em
- See CaMKII (G-1): sc-5306 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- Atualmente, ainda não concluímos a identificação do(s) reagente(s) de deteção secundário(s) preferido(s) para CAMK2A/CaMKII alpha Anticorpo (45). Este trabalho está em curso.
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory Threonine residue at position 177.
Informacoes sobre ordens
| Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
CAMK2A/CaMKII alpha Anticorpo (45) | sc-136212 | 50 µg/0.5 ml | $316.00 |