



BMPR-IB Antibody (2E2) is a mouse monoclonal IgG2a light chain antibody that detects BMPR-IB in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). BMPR-IB, also known as ALK-6, plays a crucial role in the bone morphogenetic protein (BMP) signaling pathway, which regulates various biological processes, including cell differentiation, proliferation, and apoptosis. BMPR-IB is primarily located on the cell membrane, where BMPR-IB interacts with BMPs to form a signaling complex that activates downstream serine/threonine kinases. Proper functioning of BMPR-IB is vital for maintaining normal bone development and homeostasis, as dysregulation of this pathway can lead to various pathologies, including cancer and bone disorders. BMPR-IB is expressed in several tissues, including the brain and human glioma cell lines, highlighting BMPR-IB′s importance in both normal physiology and disease states. Anti-BMPR-IB antibody (2E2) is an invaluable tool for researchers investigating the BMP signaling pathway and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BMPR-IB Antibody (2E2) | sc-293428 | 100 µg/ml | $322.00 |