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6-Hydroxy chlorzoxazone (CAS 1750-45-4)

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Alternate Names:
5-Chloro-6-hydroxybenzoxazone; 5- chloro- 6- hydroxy- 2(3H)- benzoxazolone; NSC 24955
Application:
6-Hydroxy chlorzoxazone is a major metabolite of chlorzoxazone
CAS Number:
1750-45-4
Purity:
≥97%
Molecular Weight:
185.60
Molecular Formula:
C7H4ClNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Hydroxy Chlorzoxazone is a metabolite of chlorzoxazone and plays a significant role in biochemical research, particularly in the study of xenobiotic metabolism in the liver. This compound is primarily formed through the hepatic cytochrome P450 enzyme system, which illustrates its critical utility in examining the enzyme′s function and specificity. By tracking the formation and degradation of 6-Hydroxy Chlorzoxazone, researchers can gain insights into the metabolic pathways involved in the biotransformation of xenobiotics. This is particularly valuable in the field of toxicology, where understanding these pathways is essential for assessing the metabolism and clearance of potentially toxic substances. Additionally, 6-Hydroxy Chlorzoxazone serves as a useful tool in pharmacokinetic studies, helping to elucidate the mechanisms underlying substance disposition and interaction.


6-Hydroxy chlorzoxazone (CAS 1750-45-4) References

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  7. Storage stability study of porcine hepatic and intestinal cytochrome P450 isoenzymes by use of a newly developed and fully validated highly sensitive HPLC-MS/MS method.  |  Schelstraete, W., et al. 2018. Anal Bioanal Chem. 410: 1833-1843. PMID: 29327113
  8. The Ontogeny of Cytochrome P450 Enzyme Activity and Protein Abundance in Conventional Pigs in Support of Preclinical Pediatric Drug Research.  |  Millecam, J., et al. 2018. Front Pharmacol. 9: 470. PMID: 29867477
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Hydroxy chlorzoxazone, 5 mg

sc-210516
5 mg
$640.00