Date published: 2026-7-27

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5-Benzyloxygramine (CAS 1453-97-0)

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Alternate Names:
5-Benzyloxy-3-(dimethylaminomethyl)indole; 1-[5-(Benzyloxy)-1H-indol-3-yl]-N,N-dimethylmethanamine
CAS Number:
1453-97-0
Molecular Weight:
280.36
Molecular Formula:
C18H20N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-Benzyloxygramine (5-BzG) belongs to the benzyloxygramine family of compounds. As an alkaloid, it falls under the category of natural products and can be found in several plants, such as the bark of the African tree, Acacia nilotica. Although the exact mechanism of action of 5-Benzyloxygramine is still under study, it is believed to exert its effects by interacting with the serotonin receptors responsible for regulating mood and emotions. Additionally, 5-Benzyloxygramine is thought to interact with the GABA receptors and dopamine receptors.


5-Benzyloxygramine (CAS 1453-97-0) References

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  2. Two kinds of tryptamine receptor.  |  GADDUM, JH. and PICARELLI, ZP. 1957. Br J Pharmacol Chemother. 12: 323-8. PMID: 13460238
  3. Actions of some analogues of tryptamine on the isolated rat uterus and on the isolated rat fundus strip preparations.  |  BARLOW, RB. and KHAN, I. 1959. Br J Pharmacol Chemother. 14: 99-107. PMID: 13651585
  4. Actions of some analogues of 5-hydroxytryptamine on the isolated rat uterus and the rat fundus strip preparations.  |  BARLOW, RB. and KHAN, I. 1959. Br J Pharmacol Chemother. 14: 265-72. PMID: 13662587
  5. The use of the guinea-pig ileum preparation for testing the activity of substances which imitate or antagonize the actions of 5-hydroxytryptamine and tryptamine.  |  BARLOW, RB. and KHAN, I. 1959. Br J Pharmacol Chemother. 14: 553-8. PMID: 13796840
  6. Modification by drugs of the response of the rat's uterus to adrenaline.  |  HOLZBAUER, M. and VOGT, M. 1955. Br J Pharmacol Chemother. 10: 186-90. PMID: 14389659
  7. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.  |  Lin, SM., et al. 2020. J Med Chem. 63: 3131-3141. PMID: 32105468
  8. An effective and scalable 14C radiolabelling of several biogenic indole derivatives at high specific activity.  |  Filer, CN. and Orphanos, D. 2020. Appl Radiat Isot. 165: 109268. PMID: 32858343
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  11. Role of amines in anaphylactic contraction of guinea pig isolated smooth muscle.  |  Joiner, PD., et al. 1974. J Allergy Clin Immunol. 53: 261-70. PMID: 4150792
  12. Nature of 5-HT receptors in central vasomotor loci.  |  Dhawan, KN., et al. 1967. Jpn J Pharmacol. 17: 435-8. PMID: 5300190
  13. Two kinds of tryptamine receptor. 1957.  |  Gaddum, JH. and Picarelli, ZP. 1997. Br J Pharmacol. 120: 134-9; discussion 132-3. PMID: 9142401

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Benzyloxygramine, 1 g

sc-280478
1 g
$130.00

5-Benzyloxygramine, 2.5 g

sc-280478A
2.5 g
$235.00