Date published: 2026-6-4

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Sos 1 Antibodies

Santa Cruz Biotechnology delivers a wide array of Sos 1 monoclonal antibodies for advanced research in cellular signaling pathways. Sos 1 Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Sos 1, or Son of Sevenless 1, is a guanine nucleotide exchange factor that plays a critical role in the activation of RAS proteins, which are essential for cell growth and differentiation. By mediating the exchange of GDP for GTP on RAS, Sos 1 is pivotal in transmitting signals from growth factor receptors to downstream effectors, influencing various cellular processes. Understanding the function of Sos 1 is crucial for elucidating mechanisms underlying cancer and other diseases linked to aberrant RAS signaling. Researchers worldwide rely on Sos 1 monoclonal antibodies to investigate RAS-dependent signaling cascades and their biological implications. The high specificity of Sos 1 monoclonal antibodies enables precise detection and analysis of protein interactions in complex biological systems. Santa Cruz Biotechnology monoclonal antibodies support researchers in advancing our understanding of cellular signaling pathways and their role in human health and disease.

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Sos 1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Sos 1 Antibody (A-9)

sc-17793mouse IgG2b κ1057-1178 (h)WB, IP, IF, ELISAm, r, h
10
(3)

Sos 1 Antibody (E-6)

sc-376843mouse IgG3 κC-Terminal (h)WB, IP, IF, ELISAm, r, h
2
(1)

Sos 1 Antibody (E-11)

sc-55528mouse IgG2a κ1057-1178 (h)WB, IP, IF, ELISAh
2
(3)

Sos 1 Antibody (25)

sc-136235mouse IgG11-109 (m)WB, IPm, r, h and canine

new

(1)

Sos 1 Antibody (G-12)

sc-376789mouse IgM κ1301-1333 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(2)

Sos 1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sos 1 CRISPR/Cas9 KO Plasmid (h2)

sc-401135-KO-2hGene KnockoutGFP0
(0)

Sos 1 HDR Plasmid (h2)

sc-401135-HDR-2hHomology Directed RepairPuromycin0
(0)

Sos 1 CRISPR/Cas9 KO Plasmid (m)

sc-423075mGene KnockoutGFP0
(0)

Sos 1 HDR Plasmid (m)

sc-423075-HDRmHomology Directed RepairPuromycin0
(0)

Sos 1 Double Nickase Plasmid (m)

sc-423075-NICmGene KnockoutPuromycin0
(0)

Sos 1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sos 1 CRISPR Activation Plasmid (h)

sc-401135-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sos 1 Lentiviral Activation Particles (h)

sc-401135-LAChGene ActivationPuro, Blast, Hygro0
(0)

Sos 1 CRISPR Activation Plasmid (m)

sc-423075-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Sos 1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sos 1 siRNA (h)

sc-29486hGene SilencingN/A
1
(0)

Sos 1 shRNA Plasmid (h)

sc-29486-SHhGene SilencingPuromycin
1
(0)

Sos 1 shRNA (h) Lentiviral Particles

sc-29486-VhGene SilencingPuromycin
1
(0)

Sos 1 siRNA (m)

sc-36524mGene SilencingN/A0
(0)

Sos 1 shRNA Plasmid (m)

sc-36524-SHmGene SilencingPuromycin0
(0)

Sos 1 shRNA (m) Lentiviral Particles

sc-36524-VmGene SilencingPuromycin0
(0)