LOC646405 is a provisional designation used in genomic databases for a gene locus that has not yet been fully characterized or may not correspond to a known protein-coding gene. This kind of designation is common in genomic annotation projects where automated computational tools predict the existence of a gene based on DNA sequences, but experimental evidence to confirm the gene's function, the existence of the protein, or its biological role is lacking or incomplete.
The "LOC" prefix indicates "locus," suggesting a specific location within the genome, while the numbers that follow serve as a unique identifier. In the case of LOC646405, it implies that this sequence is the 646,405th locus entered into a particular database. The annotation might be found in genomic sequencing projects such as the Human Genome Project or other organismal sequencing efforts.The characterization of such loci can involve various experimental approaches, including transcript profiling to detect RNA expression, proteomic studies to identify the protein product, and functional assays to determine the biological role of the protein. Additionally, comparative genomics can provide clues about the function of the protein by identifying homologous genes in other species.
| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Um inibidor da DNA metiltransferase, que afecta potencialmente a expressão genética, incluindo genes desconhecidos em loci específicos. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Um inibidor da histona desacetilase, com impacto na remodelação da cromatina e potencialmente influenciando a expressão genética. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Um inibidor da ROCK, que afecta as vias de sinalização da Rho GTPase. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Estabiliza os microtúbulos, afectando a divisão celular e influenciando potencialmente a função de várias proteínas. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inibe o mTOR, um regulador-chave do crescimento e da proliferação celular. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Um inibidor do proteassoma, que afecta a degradação e a renovação das proteínas. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Interage com ciclofilinas, influenciando a dobragem e a função das proteínas. | ||||||