IGFBP7 (Insulin-Like Growth Factor-Binding Protein 7) Activators constitute a distinct chemical class designed to modulate the activity of the IGFBP7 protein. IGFBP7 is a member of the IGFBP family, which binds to insulin-like growth factors (IGFs) and regulates their bioavailability and activity. Unlike some other IGFBPs that primarily serve as carriers for IGFs, IGFBP7 has emerged as a multifunctional protein involved in various biological processes beyond growth regulation. IGFBP7 Activators are compounds engineered to influence the functions of IGFBP7, thereby impacting cellular processes.
IGFBP7 is known for its role in cell growth, senescence, and apoptosis, and it has been implicated in the regulation of cellular responses to stress and tissue injury. IGFBP7 Activators are designed to either enhance or inhibit the interactions of IGFBP7 with its binding partners, such as IGFs or other proteins, by specifically targeting its binding domains or modifying its conformation. By doing so, these compounds can modulate the downstream signaling pathways that IGFBP7 is involved in, affecting cellular behavior and function. The study of IGFBP7 Activators provides valuable insights into the intricate mechanisms of cell growth and tissue homeostasis, shedding light on the broader roles of IGFBP7 in various physiological and pathological processes. Researchers are continually investigating the precise mechanisms of IGFBP7 activation and its impact on cellular biology to better understand its functions and implications in diverse biological contexts.
VEJA TAMBÉM
| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
O resveratrol aumenta a expressão de IGFBP7, reforçando potencialmente as suas funções supressoras de tumores. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Este inibidor da DNA metiltransferase pode regular positivamente o IGFBP7, afectando o ciclo celular e a supressão de tumores. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
O butirato de sódio, um inibidor da histona desacetilase, aumenta a expressão de IGFBP7, afectando a diferenciação e a proliferação celular. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
O ácido retinóico induz a expressão de IGFBP7, que pode levar à inibição do crescimento em certos tipos de células. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
O DL-Sulforafano, um composto presente nos vegetais crucíferos, pode induzir o IGFBP7, afectando a paragem do ciclo celular e a apoptose. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Encontrado no chá verde, este composto regula positivamente o IGFBP7, influenciando potencialmente a atividade anti-tumoral. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Como inibidor da histona desacetilase, regula positivamente o IGFBP7, afectando a expressão genética e os processos celulares. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Este inibidor de mTOR pode modular a expressão de IGFBP7, afectando o crescimento celular e a autofagia. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inibidor da JNK, afecta indiretamente os níveis de IGFBP7, influenciando a resposta ao stress e a apoptose. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Como inibidor da MEK, pode modular a expressão do IGFBP7, afectando as vias de sinalização celular. | ||||||