Date published: 2025-10-29

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IGFBP7 Ativadores

Os activadores comuns do IGFBP7 incluem, entre outros, o resveratrol CAS 501-36-0, a 5-azacitidina CAS 320-67-2, o butirato de sódio CAS 156-54-7, o ácido retinóico, todos os trans CAS 302-79-4 e o D,L-sulforafano CAS 4478-93-7.

IGFBP7 (Insulin-Like Growth Factor-Binding Protein 7) Activators constitute a distinct chemical class designed to modulate the activity of the IGFBP7 protein. IGFBP7 is a member of the IGFBP family, which binds to insulin-like growth factors (IGFs) and regulates their bioavailability and activity. Unlike some other IGFBPs that primarily serve as carriers for IGFs, IGFBP7 has emerged as a multifunctional protein involved in various biological processes beyond growth regulation. IGFBP7 Activators are compounds engineered to influence the functions of IGFBP7, thereby impacting cellular processes.

IGFBP7 is known for its role in cell growth, senescence, and apoptosis, and it has been implicated in the regulation of cellular responses to stress and tissue injury. IGFBP7 Activators are designed to either enhance or inhibit the interactions of IGFBP7 with its binding partners, such as IGFs or other proteins, by specifically targeting its binding domains or modifying its conformation. By doing so, these compounds can modulate the downstream signaling pathways that IGFBP7 is involved in, affecting cellular behavior and function. The study of IGFBP7 Activators provides valuable insights into the intricate mechanisms of cell growth and tissue homeostasis, shedding light on the broader roles of IGFBP7 in various physiological and pathological processes. Researchers are continually investigating the precise mechanisms of IGFBP7 activation and its impact on cellular biology to better understand its functions and implications in diverse biological contexts.

VEJA TAMBÉM

Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

O resveratrol aumenta a expressão de IGFBP7, reforçando potencialmente as suas funções supressoras de tumores.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

Este inibidor da DNA metiltransferase pode regular positivamente o IGFBP7, afectando o ciclo celular e a supressão de tumores.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

O butirato de sódio, um inibidor da histona desacetilase, aumenta a expressão de IGFBP7, afectando a diferenciação e a proliferação celular.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

O ácido retinóico induz a expressão de IGFBP7, que pode levar à inibição do crescimento em certos tipos de células.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

O DL-Sulforafano, um composto presente nos vegetais crucíferos, pode induzir o IGFBP7, afectando a paragem do ciclo celular e a apoptose.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

Encontrado no chá verde, este composto regula positivamente o IGFBP7, influenciando potencialmente a atividade anti-tumoral.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Como inibidor da histona desacetilase, regula positivamente o IGFBP7, afectando a expressão genética e os processos celulares.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Este inibidor de mTOR pode modular a expressão de IGFBP7, afectando o crescimento celular e a autofagia.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inibidor da JNK, afecta indiretamente os níveis de IGFBP7, influenciando a resposta ao stress e a apoptose.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

Como inibidor da MEK, pode modular a expressão do IGFBP7, afectando as vias de sinalização celular.