Glutamine-rich 1, also known as QRICH1, is a protein that in humans is encoded by the QRICH1 gene. This protein is characterized by a high content of glutamine residues, which are amino acids represented by the letter "Q" in protein sequences, hence the "Q-rich" designation.its glutamine-rich nature provides some clues about its potential roles. Proteins with glutamine-rich regions are often involved in protein-protein interactions and can form aggregates, which play roles in various cellular processes but can also be associated with certain diseases, such as neurodegenerative disorders.
Bioinformatic analysis suggests that QRICH1 contains a DUF3712 domain, a protein domain of unknown function found in several eukaryotic proteins. The presence of this domain suggests that QRICH1 may participate in widespread biological processes or pathways.In terms of disease associations, studies have suggested a potential link between QRICH1 and certain types of cancer. A 2020 study found that QRICH1 was upregulated in ovarian cancer tissues and that its silencing inhibited ovarian cancer cell proliferation and induced apoptosis. However, these initial findings need further validation.
VEJA TAMBÉM
| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
L-Glutamine | 56-85-9 | sc-391013 sc-391013C sc-391013A sc-391013D sc-391013B | 100 g 250 g 1 kg 5 kg 10 kg | $36.00 $46.00 $97.00 $372.00 $719.00 | 2 | |
A L-Glutamina serve de substrato primário para as proteínas ricas em glutamina, melhorando potencialmente a sua função. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
O glutamato pode ser convertido em glutamina, apoiando indiretamente as proteínas ricas em glutamina. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $61.00 | 8 | ||
O cloreto de amónio pode aumentar a síntese de glutamina, beneficiando indiretamente as proteínas ricas em glutamina. | ||||||
Azaserine | 115-02-6 | sc-29063 sc-29063A | 50 mg 250 mg | $306.00 $906.00 | 15 | |
A azaserina pode aumentar a procura celular de glutamina, activando potencialmente as vias relacionadas. | ||||||
Acivicin | 42228-92-2 | sc-200498B sc-200498C sc-200498 sc-200498D | 1 mg 5 mg 10 mg 25 mg | $102.00 $408.00 $642.00 $1275.00 | 10 | |
A Acivicina inibe a utilização da glutamina, afectando indiretamente a atividade das proteínas ricas em glutamina. | ||||||
CB 839 | 1439399-58-2 | sc-507354 | 10 mg | $140.00 | ||
O CB-839 inibe seletivamente a glutaminase, afectando o metabolismo da glutamina e as proteínas relacionadas. | ||||||
6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $41.00 $53.00 | 3 | |
O fenilbutirato pode modular os níveis de glutamina, afectando indiretamente as proteínas com domínios ricos em glutamina. | ||||||