The nomenclature FLJ20433 Activators implies a theoretical group of chemical compounds devised to enhance the activity of the protein encoded by the FLJ20433 gene. The FLJ acronym typically denotes full-length long Japan, a naming convention arising from a project aimed at discovering full-length long cDNA sequences in the Japanese population. Activators is purely speculative and does not correspond to any known chemical class. Should such a protein exist and be identified, activators would be molecules that interact with this protein to upregulate its function. These activators could potentially work by a variety of mechanisms, such as binding to the protein to stabilize its active form, increasing its expression through transcriptional regulation, or enhancing its interaction with other cellular components. The specific chemical properties of FLJ20433 Activators would depend significantly on the tertiary and quaternary structure of the FLJ20433 protein, as well as its role within the cellular machinery.
In the scenario of FLJ20433 Activators' development, the first step would be to ascertain the biological function of the FLJ20433 protein. This would likely entail a combination of genomic, proteomic, and bioinformatic techniques to map out the protein's structure, its domains of activity, and its cellular localization. Understanding the protein's role within the cell would be pivotal, and this could involve delving into its involvement in cellular processes, its interaction networks, and its regulation both at the genetic and post-translational levels. Once a comprehensive understanding of FLJ20433 is obtained, attention would turn to the chemical design of activators. These activators would be synthesized based on the structure of the protein and predicted interaction sites using computational chemistry and molecular modeling. The design process would also draw on knowledge from related proteins or homologous systems, where available. Subsequent experimental phases would involve in vitro and in vivo assays to test the compounds' efficacy in activating the FLJ20433 protein. These assays would measure not only the binding affinity and specificity of the activators but also their capacity to modulate the protein's activity in a controlled manner. Through this iterative process of hypothesis, design, synthesis, and testing, a class of FLJ20433 Activators could potentially be produced, offering insight into the biological function of the protein and serving as molecular probes for further scientific inquiry.
VEJA TAMBÉM
Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
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Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Provoca danos no ADN ao inibir a ribonucleótido redutase, induzindo potencialmente as enzimas de reparação do ADN, incluindo a EXD3. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Forma aductos de ADN que conduzem a danos no ADN, o que pode suprarregular as proteínas de reparação do ADN como a EXD3. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Induz quebras na cadeia de ADN através da inibição da topoisomerase II, possivelmente aumentando a expressão de enzimas de reparação do ADN. | ||||||
Methyl methanesulfonate | 66-27-3 | sc-250376 sc-250376A | 5 g 25 g | $55.00 $130.00 | 2 | |
Agente alquilante que provoca danos no ADN, desencadeando potencialmente a expressão das vias de reparação do ADN, incluindo a EXD3. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Uma antraciclina que se intercala no ADN, causando danos e possivelmente induzindo mecanismos de reparação do ADN. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Liga o ADN de forma cruzada, levando a um aumento da atividade de reparação do ADN que pode incluir a expressão de EXD3. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inibe a topoisomerase I, causando quebras no ADN e potencialmente aumentando a regulação das enzimas de reparação do ADN como a EXD3. | ||||||
Bleomycin | 11056-06-7 | sc-507293 | 5 mg | $270.00 | 5 | |
Induz a clivagem do ADN, aumentando potencialmente a expressão de genes envolvidos na reparação do ADN, como o EXD3. | ||||||
Benzo[a]pyrene | 50-32-8 | sc-257130 | 1 g | $439.00 | 4 | |
Um hidrocarboneto aromático policíclico que forma aductos de ADN, induzindo potencialmente a expressão de genes de reparação do ADN. | ||||||
Acrylamide Solution, 40% | 79-06-1 | sc-3721 | 1 L | $98.00 | ||
Pode formar aductos de ADN que conduzem a danos genómicos, potencialmente regulando positivamente os mecanismos de reparação do ADN, incluindo a expressão de EXD3. |