Molecular structure of Streptomycin sulfate, CAS Number: 3810-74-0
Streptomycin sulfate (CAS 3810-74-0)
See product citations (12)
Application:
Streptomycin sulfate is An antibiotic for cell culture
CAS Number:
3810-74-0
Molecular Weight:
728.69
Molecular Formula:
C21H39N7O12•1.5H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.
Streptomycin sulfate (CAS 3810-74-0) References
- Liquid chromatographic analysis of streptomycin sulfate. | Adams, E., et al. 2000. J Pharm Biomed Anal. 24: 219-26. PMID: 11130201
- Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome. | Sharma, D., et al. 2007. J Mol Biol. 374: 1065-76. PMID: 17967466
- Identification and control of impurities in streptomycin sulfate by high-performance liquid chromatography coupled with mass detection and corona charged-aerosol detection. | Holzgrabe, U., et al. 2011. J Pharm Biomed Anal. 56: 271-9. PMID: 21665399
- Technology of streptomycin sulfate separation by two-stage foam separation. | Li, J., et al. 2012. Biotechnol Prog. 28: 733-9. PMID: 22467250
- Intranasal delivery of streptomycin sulfate (STRS) loaded solid lipid nanoparticles to brain and blood. | Kumar, M., et al. 2014. Int J Pharm. 461: 223-33. PMID: 24286922
- Streptomycin ototoxicity in rat cochlear organotypic cultures. | He, JC., et al. 2015. Cell Biochem Biophys. 71: 851-6. PMID: 25352219
- Method Validation of Contact and Immersion TLC-bioautography for Determination of Streptomycin Sulfate in Shrimp. | Annuryanti, F., et al. 2020. Turk J Pharm Sci. 17: 254-258. PMID: 32636701
- Synergistic antibacterial activity of streptomycin sulfate loaded PEG-MoS2/rGO nanoflakes assisted with near-infrared. | Zhao, X., et al. 2020. Mater Sci Eng C Mater Biol Appl. 116: 111221. PMID: 32806251
- Streptomycin Sulfate-Loaded Niosomes Enables Increased Antimicrobial and Anti-Biofilm Activities. | Mansouri, M., et al. 2021. Front Bioeng Biotechnol. 9: 745099. PMID: 34778226
- Mechanism of action of streptomycin in E. coli: interruption of the ribosome cycle at the initiation of protein synthesis. | Luzzatto, L., et al. 1968. Proc Natl Acad Sci U S A. 60: 873-80. PMID: 4875806
- Use of streptomycin sulfate in the treatment of Meniere's disease. | Silverstein, H., et al. 1984. Otolaryngol Head Neck Surg. 92: 229-32. PMID: 6425780
- Ribosomal drug resistance in mycobacteria. | Sander, P., et al. 1996. Res Microbiol. 147: 59-67. PMID: 8761724
- Very high-dose streptomycin labyrinthectomy. | Sataloff, RT., et al. 1996. Ear Nose Throat J. 75: 239-43. PMID: 8935647
- Bilateral Meniere's disease. Treatment with intramuscular titration streptomycin sulfate. | Graham, MD. 1997. Otolaryngol Clin North Am. 30: 1097-100. PMID: 9386244
Inhibitor of:
AlaRS, Brucella abortus, EG665562, MRP-L20, MRP-L47, MRP-S22, Ribosomal Protein L29, Ribosomal Protein L30, Ribosomal Protein S12, Ribosomal Protein S16, RV2623 Dormancy Regulon, Salmonella paratyphi 0-2, and TTC22.Activator of:
6330403A02Rik, ESAT6, MRP-L30, MT 38 kDa antigen, Paip2b, PIEZO1, Ribosomal Protein L22, Ribosomal Protein L23, and Ribosomal Protein LP0.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Streptomycin sulfate, 10 g | sc-202821 | 10 g | $90.00 | |||
Streptomycin sulfate, 100 g | sc-202821A | 100 g | $128.00 |