Molecular structure of Zotiraciclib, CAS Number: 937270-47-8
Zotiraciclib (CAS 937270-47-8)
Alternate Names:
SB1317 TG-02 TG02 TG 02 SB-1317 SB 1317
CAS Number:
937270-47-8
Molecular Weight:
372.50
Molecular Formula:
C23H24N4O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Zotiraciclib (CAS 937270-47-8) References
- The multi-kinase inhibitor TG02 induces apoptosis and blocks B-cell receptor signaling in chronic lymphocytic leukemia through dual mechanisms of action. | Chen, R., et al. 2021. Blood Cancer J. 11: 57. PMID: 33714981
- Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas. | Wu, J., et al. 2021. Clin Cancer Res. 27: 3298-3306. PMID: 33785481
- Ponatinib, Lestaurtinib, and mTOR/PI3K Inhibitors Are Promising Repurposing Candidates against Entamoeba histolytica. | Kangussu-Marcolino, MM. and Singh, U. 2022. Antimicrob Agents Chemother. 66: e0120721. PMID: 34871094
- An overview of kinase downregulators and recent advances in discovery approaches. | Wang, B., et al. 2021. Signal Transduct Target Ther. 6: 423. PMID: 34924565
- Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib. | Pang, Y., et al. 2024. bioRxiv.. PMID: 37786680
- Synthesis and clinical application of small-molecule inhibitors of Janus kinase. | Zhang, JY., et al. 2023. Eur J Med Chem. 261: 115848. PMID: 37793326
- The promising impact of Bemcentinib and Repotrectinib on sleep impairment in Alzheimer's disease. | Ariaei, A. and Ramezani, F. 2023. J Biomol Struct Dyn. 1-17. PMID: 37909502
- Zotiraciclib (TG02) for newly diagnosed glioblastoma in the elderly or for recurrent glioblastoma: The EORTC 1608 STEAM trial. | Le Rhun, E., et al. 2024. Eur J Cancer. 198: 113475. PMID: 38159337
- Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules. | Acharya, B., et al. 2024. RSC Med Chem. 15: 399-415. PMID: 38389874
- Focus on current and emerging treatment options for glioma: A comprehensive review. | Lucke-Wold, B., et al. 2024. World J Clin Oncol. 15: 482-495. PMID: 38689623
Inhibitor of:
BC024659, BRAP, Cdx2, cyclin B, cyclin Y, Ki-67, Myc, p57, PRRT4, and ZAP-70.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Zotiraciclib, 10 mg | sc-507450 | 10 mg | $202.00 |