Zonisamide-d4 (CAS 1020720-04-0)

Zonisamide-d4 is a deuterated analogue of zonisamide, a compound extensively studied for its unique action in various research applications, particularly in the exploration of neurological function and disorders. The incorporation of deuterium atoms in place of hydrogen significantly enhances the molecular stability of zonisamide-d4, making it an invaluable tool in pharmacokinetic and metabolic studies. This modification allows scientists to trace the metabolic pathways and distribution of zonisamide in complex biological systems with greater precision, without altering its intrinsic mechanism of action. Zonisamide-d4 acts by modulating neuronal ion channels, specifically targeting sodium and calcium channels, which plays a critical role in the regulation of neurotransmitter release and neuronal excitability. This action renders it a potent molecule for investigating the intricate mechanisms underlying neuronal communication and excitability, as well as for probing the pathophysiology of neurological disorders in research models. Its utility extends further to serve as a reference standard in analytical methodologies, ensuring the accuracy and reliability of data in experimental studies focused on understanding the pharmacodynamics and pharmacokinetics of zonisamide.