ZNF85 Antibody (9A87): sc-130413

ZNF85 Antibody (9A87) is a mouse monoclonal IgG2b kappa light chain antibody that detects ZNF85 protein of human origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-ZNF85 antibody (9A87) is available as a non-conjugated format. ZNF85 protein, also known as zinc finger protein HPF4 or HTF1, belongs to the ZNF91 family and plays a crucial role in transcriptional regulation, vital for maintaining proper gene expression and cellular function. ZNF85 is predominantly localized in the nucleus, where ZNF85 exerts regulatory effects. ZNF85 contains sixteen C2H2-type zinc fingers and one KRAB domain, essential for DNA-binding capabilities and interaction with transcriptional machinery. The KRAB domain is particularly important as KRAB recruits histone-modifying proteins through interaction with KAP1, thereby influencing chromatin structure and gene accessibility. ZNF85 is highly expressed in testicular tissue, highlighting potential significance in reproductive biology and development. ZNF85′s ability to modulate transcriptional activity underscores importance in various biological processes, including cell differentiation and response to environmental signals.

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ZNF85 Antibody (9A87) References:

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