ZNF596 Antibody (3302D3a): sc-81146

ZNF596 Antibody (3302D3a) is a mouse monoclonal IgG1 antibody that detects the ZNF596 protein of human origin by western blotting (WB) and immunoprecipitation (IP). Anti-ZNF596 antibody (3302D3a) is available as a non-conjugated format. ZNF596 is a member of the Krüppel C2H2-type zinc-finger protein family, characterized by its 11 C2H2-type zinc fingers and a single KRAB domain, which is crucial for function in transcriptional regulation. ZNF596 is primarily located in the nucleus, where ZNF596 plays a significant role in modulating gene expression by interacting with DNA and other regulatory proteins. The presence of the KRAB domain allows ZNF596 to recruit histone-modifying proteins, thereby influencing chromatin structure and accessibility, which is essential for proper transcriptional activation or repression. ZNF596 undergoes alternative splicing, resulting in three distinct isoforms, each potentially having unique regulatory roles in cellular processes. Understanding the function and interactions of ZNF596 is vital, as dysregulation of zinc-finger proteins has been implicated in various diseases, including cancer, making ZNF596 (3302D3a) antibody a valuable tool for research in gene regulation and disease mechanisms.

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ZNF596 Antibody (3302D3a) References:

1. Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.  |  de Leeuw, RJ., et al. 2004. Hum Mol Genet. 13: 1827-37. PMID: 15229187
2. The SCAN domain family of zinc finger transcription factors.  |  Edelstein, LC. and Collins, T. 2005. Gene. 359: 1-17. PMID: 16139965
3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.  |  Kimura, K., et al. 2006. Genome Res. 16: 55-65. PMID: 16344560
4. DNA sequence and analysis of human chromosome 8.  |  Nusbaum, C., et al. 2006. Nature. 439: 331-5. PMID: 16421571
5. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.  |  O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
6. Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity.  |  Zhong, Z., et al. 2007. J Biochem Mol Biol. 40: 517-24. PMID: 17669267

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF596 Antibody (3302D3a) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF596 Antibody (3302D3a) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF596 Antibody (3302D3a) Specifications

Alternate Product Name: ZNF596

Product Clone Name: 3302D3a

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: ZNF596

Epitope Species: human

Product Reactivity/Detection: ZNF596

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF596 Antibody (3302D3a): N/A