Date published: 2025-11-4

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ZnAF-1F (CAS 443302-08-7)

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Alternate Names:
5-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2′,7′-difluorofluorescein
Application:
ZnAF-1F is a probe for fluorimetric detection of zinc
CAS Number:
443302-08-7
Molecular Weight:
608.59
Molecular Formula:
C34H26F2N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Suitable for the fluorimetric detection of Zn2+.


ZnAF-1F (CAS 443302-08-7) References

  1. Improvement and biological applications of fluorescent probes for zinc, ZnAFs.  |  Hirano, T., et al. 2002. J Am Chem Soc. 124: 6555-62. PMID: 12047174
  2. A novel, cell-permeable, fluorescent probe for ratiometric imaging of zinc ion.  |  Maruyama, S., et al. 2002. J Am Chem Soc. 124: 10650-1. PMID: 12207508
  3. Synthetic fluorescent sensors for studying the cell biology of metals.  |  Domaille, DW., et al. 2008. Nat Chem Biol. 4: 168-75. PMID: 18277978
  4. Metals in neurobiology: probing their chemistry and biology with molecular imaging.  |  Que, EL., et al. 2008. Chem Rev. 108: 1517-49. PMID: 18426241
  5. Loss of pluripotency in human embryonic stem cells directly correlates with an increase in nuclear zinc.  |  Wolford, JL., et al. 2010. PLoS One. 5: e12308. PMID: 20808840
  6. Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols.  |  Hyman, LM. and Franz, KJ. 2012. Coord Chem Rev. 256: 2333-2356. PMID: 23440254
  7. Fluorescent sensors for measuring metal ions in living systems.  |  Carter, KP., et al. 2014. Chem Rev. 114: 4564-601. PMID: 24588137
  8. Development of Functional Fluorescent Molecular Probes for the Detection of Biological Substances.  |  Suzuki, Y. and Yokoyama, K. 2015. Biosensors (Basel). 5: 337-63. PMID: 26095660
  9. ZIP8 exacerbates collagen-induced arthritis by increasing pathogenic T cell responses.  |  Kang, JA., et al. 2021. Exp Mol Med. 53: 560-571. PMID: 33795795
  10. Tailoring tripodal ligands for zinc sensing.  |  Dai, Zhaohua and James W. Canary. 2007. New Journal of Chemistry. 31.10: 1708-1718.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

ZnAF-1F, 1 mg

sc-216073
1 mg
$151.00

ZnAF-1F, 5 mg

sc-216073A
5 mg
$755.00

ZnAF-1F, 25 mg

sc-216073B
25 mg
$2244.00