Date published: 2026-4-27

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Zn(II) Mesoporphyrin IX (CAS 14354-67-7)

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Alternate Names:
Zinc hydrogen 3,3′-(7,13-diethyl-3,8,12,17-tetramethylporphine-21,24-diide-2,18-diyl)dipropanoate (1:2:1)
Application:
Zn(II) Mesoporphyrin IX is a natural zinc (II) porphyrin derivative
CAS Number:
14354-67-7
Purity:
≥95%
Molecular Weight:
630.06
Molecular Formula:
C34H36N4O4•Zn
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Zn(II) Mesoporphyrin IX is a synthetic porphyrin complex in which a zinc ion is coordinated in the center of the mesoporphyrin IX structure. Mesoporphyrin IX is a derivative of heme, the iron-containing porphyrin complex that forms an essential part of hemoglobin. In Zn(II) Mesoporphyrin IX, the iron normally found in the heme is replaced by zinc, significantly altering the compound′s properties and potential applications. Zinc porphyrins typically show strong absorbance in the visible range, making them useful as dyes or indicators. They are also explored in applications that require light absorption, such as solar energy capture. Zn(II) Mesoporphyrin IX can be used as a photosensitizer. The compound is activated by light of a specific wavelength, leading to the production of reactive oxygen species that can kill cells or microbes locally.


Zn(II) Mesoporphyrin IX (CAS 14354-67-7) References

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  2. Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis.  |  Gnana-Prakasam, JP., et al. 2011. Invest Ophthalmol Vis Sci. 52: 9279-86. PMID: 22058337
  3. Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.  |  Huynh, C., et al. 2012. PLoS Pathog. 8: e1002795. PMID: 22807677
  4. A membrane-bound eIF2 alpha kinase located in endosomes is regulated by heme and controls differentiation and ROS levels in Trypanosoma cruzi.  |  da Silva Augusto, L., et al. 2015. PLoS Pathog. 11: e1004618. PMID: 25658109
  5. The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake.  |  Merli, ML., et al. 2016. PLoS Negl Trop Dis. 10: e0004359. PMID: 26752206
  6. A new model for Trypanosoma cruzi heme homeostasis depends on modulation of TcHTE protein expression.  |  Pagura, L., et al. 2020. J Biol Chem. 295: 13202-13212. PMID: 32709751
  7. Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome.  |  Wijnsma, KL., et al. 2020. Front Immunol. 11: 547406. PMID: 33414780
  8. The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.  |  Fiorito, V., et al. 2021. Cell Rep. 35: 109252. PMID: 34133926
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Zn(II) Mesoporphyrin IX, 25 mg

sc-396862
25 mg
$213.00