Molecular structure of ZM 226600, CAS Number: 147695-92-9
ZM 226600 (CAS 147695-92-9)
Application:
ZM 226600 is a potent Kir6 (KATP) channel opener
CAS Number:
147695-92-9
Purity:
≥98%
Molecular Weight:
373.35
Molecular Formula:
C16H14F3NO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
ZM 226600 is a potent KIR (Kir6, KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.
ZM 226600 (CAS 147695-92-9) References
- The inhibitory effect of adrenomedullin in the rat ileum: cross-talk with beta3-adrenoceptor in the serotonin-induced muscle contraction. | Kravtsov, GM., et al. 2004. J Pharmacol Exp Ther. 308: 241-8. PMID: 14569072
- KATP channel openers: structure-activity relationships and therapeutic potential. | Mannhold, R. 2004. Med Res Rev. 24: 213-66. PMID: 14705169
- Inhibitory effects of different ATP-sensitive potassium channel openers on electrically generated and carbachol-induced contractions of porcine and human detrusor muscle. | Badawi, JK., et al. 2008. Fundam Clin Pharmacol. 22: 75-86. PMID: 18251724
- Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol-response curve in porcine detrusor muscle. | Badawi, JK., et al. 2012. Arab J Urol. 10: 207-15. PMID: 26558027
Activator of:
KIR, and KIR6.1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZM 226600, 10 mg | sc-281189 | 10 mg | $100.00 | |||
ZM 226600, 50 mg | sc-281189A | 50 mg | $348.00 |