Date published: 2025-10-21

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Zinc bromide (CAS 7699-45-8)

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Application:
Zinc bromide is a compound used as a lewis acid in organic chemistry
CAS Number:
7699-45-8
Molecular Weight:
225.20
Molecular Formula:
ZnBr2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Zinc bromide (ZnBr2) holds significant importance in scientific research due to its diverse properties and wide-ranging applications across various disciplines. One of its primary mechanisms of action lies in its role as a Lewis acid catalyst. Zinc bromide′s ability to accept electron pairs from other molecules makes it invaluable in catalyzing a variety of organic transformations. In organic synthesis, zinc bromide facilitates reactions such as Friedel-Crafts acylations, alkylations, and rearrangements by activating electrophilic substrates and stabilizing reaction intermediates. Moreover, zinc bromide finds extensive use in the field of materials science, where it serves as a key component in the synthesis of zinc-based materials and nanocomposites. Its ability to form stable coordination complexes with organic ligands enables the preparation of functionalized nanoparticles and hybrid materials with tailored properties for applications in catalysis, sensing, and energy storage. Additionally, research efforts have explored its potential in electrochemistry, where it is utilized as an electrolyte in batteries and electrochemical cells. Furthermore, zinc bromide is employed in analytical chemistry as a reagent for the determination and quantification of certain analytes. Its reaction with specific functional groups, such as alcohols and amines, enables their derivatization and subsequent analysis via chromatographic or spectroscopic techniques. Overall, zinc bromide continues to be a versatile and indispensable tool in scientific investigations, owing to its diverse functionalities and broad utility in research applications spanning organic synthesis, materials science, electrochemistry, and analytical chemistry.


Zinc bromide (CAS 7699-45-8) References

  1. An Efficient one-pot Biginelli condensation of aliphatic aldehydes catalyzed by zinc bromide under solvent-free conditions.  |  Yu, Y., et al. 2007. Prep Biochem Biotechnol. 37: 381-7. PMID: 17849292
  2. Palladium-catalyzed cross-coupling of cyclopropylmagnesium bromide with aryl bromides mediated by zinc halide additives.  |  Shu, C., et al. 2010. J Org Chem. 75: 6677-80. PMID: 20815373
  3. Zinc bromide promoted coupling of isonitriles with carboxylic acids to form 2,4,5-trisubstituted oxazoles.  |  Odabachian, Y., et al. 2013. Angew Chem Int Ed Engl. 52: 10878-82. PMID: 23959698
  4. An efficient method for the construction of polysubstituted 4-pyridones via self-condensation of β-keto amides mediated by P2O5 and catalyzed by zinc bromide.  |  Tan, L., et al. 2013. Beilstein J Org Chem. 9: 2681-7. PMID: 24367433
  5. Passerini Reactions on Biocatalytically Derived Chiral Azetidines.  |  Moni, L., et al. 2016. Molecules. 21: PMID: 27589709
  6. Oxidative Carboxylation of 1-Decene to 1,2-Decylene Carbonate.  |  Engel, RV., et al. 2018. Top Catal. 61: 509-518. PMID: 31258305
  7. Hydrosilane-Mediated Electrochemical Reduction of Amides.  |  Okamoto, K., et al. 2021. J Org Chem. 86: 15992-16000. PMID: 34152146
  8. Oligo(amylene) from the reaction of fusel oil with zinc dihalide.  |  Davis, MC., et al. 2021. RSC Adv. 11: 1960-1968. PMID: 35747216
  9. Synthesis of β-Allenylamines by Addition of Chloroprene Grignards to N-Boc Imines.  |  Geissler, AGA. and Breit, B. 2022. Org Lett. 24: 7967-7971. PMID: 36278859
  10. A submillimeter bundled microtubular flow battery cell with ultrahigh volumetric power density.  |  Wu, Y., et al. 2023. Proc Natl Acad Sci U S A. 120: e2213528120. PMID: 36595700

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Zinc bromide, 100 g

sc-203416
100 g
$54.00

Zinc bromide, 500 g

sc-203416A
500 g
$152.00

Zinc bromide, 1 kg

sc-203416B
1 kg
$265.00

Zinc bromide, 5 kg

sc-203416C
5 kg
$950.00