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Molecular structure of Zinc bis[bis(trimethylsilyl)amide], CAS Number: 14760-26-0
Zinc bis[bis(trimethylsilyl)amide] (CAS 14760-26-0)
Alternate Names:
Zinc, bis(hexamethyldisilylamide); 1,1,1,3,3,3-Hexamethyldisilazane zinc salt; Zinc bis(hexamethyldisilazide)
CAS Number:
14760-26-0
Molecular Weight:
386.16
Molecular Formula:
C12H36N2Si4Zn
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Zinc bis[bis(trimethylsilyl)amide], otherwise known as BBTSZn, has been utilized as a catalyst in organic synthesis, a reagent in research aimed at drug creation, and an investigative tool in biochemical and physiological studies. Additionally, it′s used to study protein-ligand interactions and to examine enzyme inhibition and activation. The mechanism of Zinc bis[bis(trimethylsilyl)amide] involves binding to zinc-binding proteins. This binding instigates a conformational change in the protein, leading to alterations in the protein′s activity. This action mechanism is harnessed in various biochemical and physiological studies.
Zinc bis[bis(trimethylsilyl)amide] (CAS 14760-26-0) References
- pH-responsive biodegradable micelles based on acid-labile polycarbonate hydrophobe: synthesis and triggered drug release. | Chen, W., et al. 2009. Biomacromolecules. 10: 1727-35. PMID: 19469499
- Galactose-decorated cross-linked biodegradable poly(ethylene glycol)-b-poly(ε-caprolactone) block copolymer micelles for enhanced hepatoma-targeting delivery of paclitaxel. | Yang, R., et al. 2011. Biomacromolecules. 12: 3047-55. PMID: 21726090
- Novel injectable biodegradable glycol chitosan-based hydrogels crosslinked by Michael-type addition reaction with oligo(acryloyl carbonate)-b-poly(ethylene glycol)-b-oligo(acryloyl carbonate) copolymers. | Yu, Y., et al. 2011. J Biomed Mater Res A. 99: 316-26. PMID: 21887740
- Core-crosslinked pH-sensitive degradable micelles: A promising approach to resolve the extracellular stability versus intracellular drug release dilemma. | Wu, Y., et al. 2012. J Control Release. 164: 338-45. PMID: 22800578
- Facile construction of dual-bioresponsive biodegradable micelles with superior extracellular stability and activated intracellular drug release. | Chen, W., et al. 2015. J Control Release. 210: 125-33. PMID: 25987525
- Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: A robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy. | Zou, Y., et al. 2016. J Control Release. 244: 326-335. PMID: 27245309
- Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(ε-caprolactone) micelles. | Fang, Y., et al. 2017. Acta Biomater. 50: 396-406. PMID: 28065871
- Stereoselective photoredox ring-opening polymerization of O-carboxyanhydrides. | Feng, Q., et al. 2018. Nat Commun. 9: 1559. PMID: 29674720
- Encapsulation of Thermo-responsive Gel in pH-sensitive Polymersomes as Dual-Responsive Smart carriers for Controlled Release of Doxorubicin. | Oroojalian, F., et al. 2018. J Control Release. 288: 45-61. PMID: 30171978
- Cyclic RGD-Functionalized and Disulfide-Crosslinked Iodine-Rich Polymersomes as a Robust and Smart Theranostic Agent for Targeted CT Imaging and Chemotherapy of Tumor. | Zou, Y., et al. 2019. Theranostics. 9: 8061-8072. PMID: 31754381
- Biodegradable glycopolymer-b-poly(ε-caprolactone) block copolymer micelles: versatile construction, tailored lactose functionality, and hepatoma-targeted drug delivery. | Chen, W., et al. 2015. J Mater Chem B. 3: 2308-2317. PMID: 32262061
- Injectable and thermosensitive hydrogels mediating a universal macromolecular contrast agent with radiopacity for noninvasive imaging of deep tissues. | Wu, X., et al. 2021. Bioact Mater. 6: 4717-4728. PMID: 34136722
- Synthesis, solution dynamics and chemical vapour deposition of heteroleptic zinc complexes via ethyl and amide zinc thioureides. | Bhide, MA., et al. 2021. Chem Sci. 12: 8822-8831. PMID: 34257883
- A Single Catalyst for Promoting Reverse Processes: Synthesis and Chemical Degradation of Polylactide. | Santulli, F., et al. 2021. ChemSusChem. 14: 5470-5475. PMID: 34612598
- Synthesis and Crystal Structures of Dinuclear Zinc Complexes with the 3,5-Bis(pyridine-2-yl)pyrazolato Ligand | Tobias Kloubert, Helmar Görls, Prof. Dr. Matthias Westerhausen. November 2010. Wiley Online Library. 636: 2405-2408.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Zinc bis[bis(trimethylsilyl)amide], 1 g | sc-224452 | 1 g | $485.00 | |||
| US: Only available in the US | ||||||