Z-His(Bzl)-OH (CAS 21929-66-8)
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Z-His(Bzl)-OH is a derivative of histidine, an amino acid that plays a vital role in various physiological processes. It acts as a competitive inhibitor of various enzymes and receptors, including proteases, kinases, and G protein-coupled receptors. It has allosteric effects, modulating the activity of enzymes and receptors by binding to sites other than the active site. It has also been shown to modulate the activity of ion channels and have antioxidant properties. Z-His(Bzl)-OH is used in various scientific research applications, including peptide synthesis, protein engineering, and drug discovery. It serves as a building block for the synthesis of peptides and proteins, which are essential in studying the structure and function of various biological molecules.
Z-His(Bzl)-OH (CAS 21929-66-8) References
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- Doxorubicin-loaded polymeric micelle overcomes multidrug resistance of cancer by double-targeting folate receptor and early endosomal pH. | Kim, D., et al. 2008. Small. 4: 2043-50. PMID: 18949788
- Triptorelin Tethered Multifunctional PAMAM-Histidine-PEG Nanoconstructs Enable Specific Targeting and Efficient Gene Silencing in LHRH Overexpressing Cancer Cells. | Tambe, P., et al. 2017. ACS Appl Mater Interfaces. 9: 35562-35573. PMID: 28949503
- Targeted silencing of the MCL-1 gene using multi-layered dendrimer-based nanoconstructs achieves efficient tumor regression in xenografted mice models. | Tambe, P., et al. 2023. Int J Pharm. 634: 122659. PMID: 36720446
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Z-His(Bzl)-OH, 1 g | sc-224424 | 1 g | $288.00 |