(Z-DEVD)2-R110 MW: 1515.44
Strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.

(Z-DEVD)2-R110

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Application: (Z-DEVD)2-R110 is strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm
Molecular Weight: 1515.44
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Since highly purified rhodamine 110 (R110)-derived substrates are locked in the lactone configuration they are colorless and non-fluorescent. Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments. R110-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. This R110 substrate is specific for caspases 3 and 7. Our R110-based substrates are highly purified to eliminate the trace amount of free R110 that is not detectable by HPLC, but causes significant assay background.

Physical State :
Solid
Storage :
Desiccate at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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