(Z-DEVD)2-R110
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(Z-DEVD)2-R110 is a compound designed for biochemical and cell biology research, particularly in the context of studying caspase activity. It is a fluorogenic substrate designed for the detection and quantification of caspase activity, specifically caspase-3 and capsase-7, which are critical executioner enzymes in the process of apoptosis, or programmed cell death. The Z (Benzyloxycarbonyl) is a protective group used to block the amino terminus of the first aspartic acid residue, enhancing the substrate′s specificity for caspase-3 and capsase-7. R110 is a fluorescent reporter molecule attached to the DEVD peptides. It is a green-fluorescent dye that increases in fluorescence intensity upon cleavage by caspase-3 and capsase-7. The use of (Z-DEVD)2-R110 in research allows for the direct observation and quantification of caspase-3 and capsase-7 activity in various experimental applications.
(Z-DEVD)2-R110 References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(Z-DEVD)2-R110, 1 mg | sc-477255 | 1 mg | $104.00 |