(Z-Asp-Glu-Val-Asp)2-Rh110 (CAS 220846-75-3)
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Alternate Names:
(Z-DEVD)2-Rh110; Caspase 3 (Apopain) Substrate 1r-z
Application:
(Z-Asp-Glu-Val-Asp)2-Rh110 is a substrate for caspase 3
CAS Number:
220846-75-3
Molecular Weight:
1515.48
Molecular Formula:
C72H78N10O27
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(Z-Asp-Glu-Val-Asp)2-Rh110, also known as Caspase 3 (Apopain) Substrate 1r-z is a fluorogenic substrate for caspase 3. Rh110 (Rhodamine 110)-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. Cleavage of Rh110 peptides by caspases generates strongly fluorescent Rh110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments.
(Z-Asp-Glu-Val-Asp)2-Rh110 (CAS 220846-75-3) References
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- Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease. | Totzke, J., et al. 2017. Cell Chem Biol. 24: 1029-1039.e7. PMID: 28820959
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Substrate of:
caspase-3, and caspase-7.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(Z-Asp-Glu-Val-Asp)2-Rh110, 1 mg | sc-391024 | 1 mg | $41.00 | |||
(Z-Asp-Glu-Val-Asp)2-Rh110, 5 mg | sc-391024A | 5 mg | $224.00 |